TACR1

Gene Symbol TACR1
Entrez Gene 6869
Alt Symbol NK1R, NKIR, SPR, TAC1R
Species Human
Gene Type protein-coding
Description tachykinin receptor 1
Other Description NK-1 receptor|NK-1R|substance-P receptor|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
Swissprots P25103 A8K150
Accessions AAY14950 AAY15031 CAA46292 EAW99595 EAW99596 P25103 AK289765 BAF82454 AW206679 AY462098 AAR23925 BC074911 AAH74911 BC074912 AAH74912 BC095528 AAH95528 DB203452 M74290 AAA60601 M76675 AAA59936 M81797 AAA59933 M84425 AAA36641 M84426 AAA36644 S62045 AAB20168 NM_001058 NP_001049 NM_015727 NP_056542
Function This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Top Pathways Calcium signaling pathway, Measles, Neuroactive ligand-receptor interaction

NK-1R (D-11) - sc-365091 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NK-1R (D-11): sc-365091. Western blot analysis of NK-1R expression in WEHI-3 (A), K-562 (B) and CCD-1064Sk (C) whole cell lysates.

NK-1R (F-3) - sc-514453 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NK-1R (F-3): sc-514453. Western blot analysis of NK-1R expression in K-562 (A), Jurkat (B), HL-60 (C) and U-937 (D) whole cell lysates.

NK-1R (H-83) - sc-15323 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

NK-1R (K-18) - sc-14116 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NK-1R (K-18): sc-14116. Western blot analysis of NK-1R expression in U-937 (A) and WEHI-231 (B) whole cell lysates.

NK-1R (L-15) - sc-14115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NK-1R (L-15): sc-14115. Western blot analysis of NK-1R expression in mouse pancreas tissue extract.

NK-1R (N-19) - sc-5218 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NK-1R (N-19): sc-5218. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pre-menopausal uterus tissue showing cytoplasmic staining of glandular cells and cells in endometrial stroma.

NK-1R (T-20) - sc-5220 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NK-1R (T-20): sc-5220. Western blot analysis of NK-1R expression in K-562 (A), Jurkat (B) and HL-60 (C) whole cell lysates.

Anti-Neurokinin 1 Receptor antibody - ab75516 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Neurokinin 1 Receptor antibody (ab75516) at 1/500 dilutionLane 1 : Jurkat cell extractLane 2 : Jurkat cell extract with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Neurokinin 1 Receptor antibody - ab131091 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Neurokinin 1 Receptor antibody - ab139323 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Neurokinin 1 Receptor antibody (ab139323) at 1/500 dilution + Jurkat total cell extract

Anti-Neurokinin 1 Receptor antibody - ab466 from Abcam

Prices $373.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Neurokinin 1 Receptor antibody [EPR6836(2)] - ab183713 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6836(2)
Western blot analysis of Neurokinin 1 Receptor in K562 cell lysate immunoprecipitated using ab183713 at 1/50 dilution (Lane 1). Lane 2 : TBS instead of K562 lysates.Secondary antibody: Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1500 dilution

Anti-TACR1 / NK1R Antibody (N-Terminus) IHC-plus™ - LS-B500 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Neurokinin 1 Receptor antibody IHC of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B500 concentration 10 ug/ml.

Anti-TACR1 / NK1R Antibody (C-Terminus) IHC-plus™ - LS-A1342 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Neurokinin 1 Receptor antibody LS-A1342 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TACR1 / NK1R Antibody (Extracellular Domain) IHC-plus™ - LS-A1339 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Neurokinin 1 Receptor antibody LS-A1339 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TACR1 / NK1R Antibody (aa385-407) - LS-C39304 from LifeSpan Bioscience

Prices $560.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody - LS-C39305 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody (C-Terminus) - LS-C39306 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody (C-Terminus) - LS-C39307 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody - LS-C39308 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody (aa385-407) - LS-C76144 from LifeSpan Bioscience

Prices $515.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody (N-Terminus, Biotin) - LS-C142044 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody (N-Terminus, DY650) - LS-C142045 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody (N-Terminus, DY488) - LS-C142046 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TACR1 / NK1R Antibody (N-Terminus, HRP) - LS-C142047 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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