Gene Symbol | CBX1 |
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Entrez Gene | 10951 |
Alt Symbol | CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta |
Species | Human |
Gene Type | protein-coding |
Description | chromobox homolog 1 |
Other Description | HP1 beta homolog|chromobox homolog 1 (HP1 beta homolog Drosophila )|chromobox protein homolog 1|heterochromatin protein 1 homolog beta|heterochromatin protein 1-beta|heterochromatin protein p25 beta|modifier 1 protein |
Swissprots | P23197 P83916 |
Accessions | AAD21972 EAW94758 EAW94759 EAW94760 EAW94761 P83916 AK312615 BAG35502 BC002609 AAH02609 BC021302 AAH21302 CB053834 CR456766 CAG33047 DA020204 DA689514 DA781730 DB026977 EU446771 ABZ92300 U35451 AAB81548 NM_001127228 NP_001120700 NM_006807 NP_006798 |
Function | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10460410, ECO:0000269|PubMed:9169582}. Note=Unassociated with chromosomes during mitosis. |
Tissue Specificity | Expressed in all adult and embryonic tissues. |
CBX1 / HP1 beta peptide - ab30861 from Abcam
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CBX1 / HP1 beta peptide - ab45825 from Abcam
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Human CBX1 / HP1 beta full length protein - ab109847 from Abcam
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Human CBX1 / HP1 beta full length protein - ab198680 from Abcam
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CBX1 / HP1 Beta Antibody Blocking Peptide - LS-E12202 from LifeSpan Bioscience
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CBX1 / HP1 Beta Antibody Blocking Peptide - LS-E12203 from LifeSpan Bioscience
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CBX1 / HP1 Beta Antibody Blocking Peptide - LS-E25965 from LifeSpan Bioscience
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CBX1 / HP1 Beta Antibody Blocking Peptide - LS-E9851 from LifeSpan Bioscience
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CBX1 Recombinant Protein - H00010951-P01 from Novus Biologicals
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CBX1 Partial Recombinant Protein - H00010951-Q01 from Novus Biologicals
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Recombinant Human CBX1 Protein - NBP1-72359 from Novus Biologicals
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CBX1-Antibody-C-term-Blocking-peptide - BP13741b from Abgent, a WuXi AppTec company
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CBX1-Antibody-C-term-Blocking-Peptide - BP8915c from Abgent, a WuXi AppTec company
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CBX1 / HP1 beta blocking peptide - GTX89455-PEP from GeneTex
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CBX1 Protein (OPPA00147) - OPPA00147 from Aviva Systems Biology
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Human CBX1 protein - orb168045 from Biorbyt
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CBX1 protein (His tag) - 80R-1871 from Fitzgerald
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CBX1 / HP1 beta Peptide - AC21-0792-P from Abcore
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CBX1 (1-185, His-tag) - AR39053PU-L from Acris Antibodies
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CBX1 (1-185, His-tag) - AR39053PU-N from Acris Antibodies
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CBX1 - H00010951-P01-10 from Acris Antibodies
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CBX1 - H00010951-P01-25 from Acris Antibodies
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CBX1 - H00010951-Q01-10 from Acris Antibodies
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CBX1 - H00010951-Q01-25 from Acris Antibodies
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Chromobox Homolog 1, Human Recombinant - 228-13315-1 from RayBiotech
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