PAPD7

Gene Symbol	PAPD7
Entrez Gene	11044
Alt Symbol	LAK-1, LAK1, POLK, POLS, TRF4, TRF4-1, TRF41, TUTASE5
Species	Human
Gene Type	protein-coding
Description	PAP associated domain containing 7
Other Description	DNA polymerase kappa|DNA polymerase sigma|PAP-associated domain-containing protein 7|TRAMP-like complex polyadenylate polymerase|TUTase 5|non-canonical poly(A) RNA polymerase PAPD7|polymerase (DNA directed) sigma|polymerase (DNA-directed) sigma|terminal uridylyltransferase 5|topoisomerase-related function protein 4-1
Swissprots	Q17RZ1 A8K1E2 Q5XG87 M1JCE6 Q9Y6C1 O43289
Accessions	AAT38110 EAX08101 Q5XG87 AB005754 BAA24434 AF089896 AAD45198 AI871781 AK289857 BAF82546 AK303516 BAG64545 AK308405 BC084567 AAH84567 BC117137 AAI17138 BC126106 AAI26107 BC143882 AAI43883 HQ258305 ADR83059 KC424495 AGE92663 R49553 XM_005248234 XP_005248291 XM_011513945 XP_011512247 XM_011513946 XP_011512248 XM_011513947 XP_011512249 NM_001171805 NP_001165276 NM_001171806 NP_001165277 NM_006999 NP_008930
Function	Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation. {ECO:0000269|PubMed:23376078}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:23376078}. Nucleus, nucleoplasm {ECO:0000269|PubMed:23376078}. Note=Excluded from nucleolus, weak staining detected in the cytoplasm.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TRF41 full length protein - ab161264 from Abcam Category Protein Source Wheat germ Species Human

Human TRF41 protein fragment - ab161265 from Abcam Category Protein Source Wheat germ Species Human

PAPD7 / TRF4-1 Antibody Blocking Peptide - LS-E4568 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAPD7 / TRF4-1 Antibody Blocking Peptide - LS-E17614 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLK Antibody Blocking Peptide - LS-E17639 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLK Antibody Blocking Peptide - LS-E17640 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DNA polymerase sigma Protein - H00011044-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human DNA polymerase sigma Protein - H00011044-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human DNA Polymerase Kappa Protein - H00051426-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

POLS-Antibody-Center-Blocking-Peptide - BP16915c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

POLK Blocking Peptide - 33R-4442 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

POLK Blocking Peptide - 33R-1553 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

POLS Blocking Peptide - 33R-9878 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PAPD7 / POLS / TRF4 - H00011044-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PAPD7 / POLS / TRF4 - H00011044-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PAPD7 / POLS / TRF4 - H00011044-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

POLS fusion protein - ag18849 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

POLS fusion protein - ag18594 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Human nemo-like kinase / NLK Protein (His & GST Tag) - 11573-H20B-100 from Sino Biological Category Protein Prices $198.00, $258.00 Sizes 20 µg, 50 µg Source Baculovirus-Insect Cells Species Human

Recombinant Human DNA polymerase sigma(PAPD7) - CSB-YP733396HU CSB-EP733396HU CSB-BP733396HU CSB-MP733396HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Human nemo-like kinase / NLK Protein (His & GST Tag) - 11573-H20B-50 from Sino Biological Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human nemo-like kinase / NLK Protein (His & GST tag) - PKSH030360 from Elabscience Category Protein Source Baculovirus-Insect Cells Species Human

DNA polymerase sigma Recombinant Protein Antigen - NBP2-13729PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DNA polymerase sigma Recombinant Protein Antigen - NBP2-13728PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PAPD7 Peptide, Human - M34GP11285H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more