PAPD7

Gene Symbol	PAPD7
Entrez Gene	11044
Alt Symbol	LAK-1, LAK1, POLK, POLS, TRF4, TRF4-1, TRF41, TUTASE5
Species	Human
Gene Type	protein-coding
Description	PAP associated domain containing 7
Other Description	DNA polymerase kappa|DNA polymerase sigma|PAP-associated domain-containing protein 7|TRAMP-like complex polyadenylate polymerase|TUTase 5|non-canonical poly(A) RNA polymerase PAPD7|polymerase (DNA directed) sigma|polymerase (DNA-directed) sigma|terminal uridylyltransferase 5|topoisomerase-related function protein 4-1
Swissprots	Q17RZ1 A8K1E2 Q5XG87 M1JCE6 Q9Y6C1 O43289
Accessions	AAT38110 EAX08101 Q5XG87 AB005754 BAA24434 AF089896 AAD45198 AI871781 AK289857 BAF82546 AK303516 BAG64545 AK308405 BC084567 AAH84567 BC117137 AAI17138 BC126106 AAI26107 BC143882 AAI43883 HQ258305 ADR83059 KC424495 AGE92663 R49553 XM_005248234 XP_005248291 XM_011513945 XP_011512247 XM_011513946 XP_011512248 XM_011513947 XP_011512249 NM_001171805 NP_001165276 NM_001171806 NP_001165277 NM_006999 NP_008930
Function	Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation. {ECO:0000269|PubMed:23376078}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:23376078}. Nucleus, nucleoplasm {ECO:0000269|PubMed:23376078}. Note=Excluded from nucleolus, weak staining detected in the cytoplasm.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TRF4 CRISPR/Cas9 KO Plasmid (h) - sc-411556 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TRF4 HDR Plasmid (h) - sc-411556-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TRF4 Double Nickase Plasmid (h) - sc-411556-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TRF4 Double Nickase Plasmid (h2) - sc-411556-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TRF4 CRISPR Activation Plasmid (h) - sc-411556-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TRF4 CRISPR Activation Plasmid (h2) - sc-411556-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TRF4 Lentiviral Activation Particles (h) - sc-411556-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TRF4 Lentiviral Activation Particles (h2) - sc-411556-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TRF4 siRNA (h) - sc-91936 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TRF4 shRNA Plasmid (h) - sc-91936-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TRF4 shRNA (h) Lentiviral Particles - sc-91936-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

DNA polymerase sigma RNAi - H00011044-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

DNA Polymerase Kappa RNAi - H00051426-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

DNA polymerase sigma RNAi - H00011044-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU118851 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16313 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16313 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10924 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10924

PAPD7 siRNA (Human) - CRH7547 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PAPD7 (NM_006999.4) - SHH370472 from Creative biogene Category siRNA Species Reactivities Human

Human PAPD7 siRNA - orb268049 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PAPD7 shRNA Plasmid (Human) - CHH7547 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PAPD7 miRNA 3'UTR clone - MiUTR4H-TG06411 from Creative biogene Species Reactivities Human

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