MLANA

Gene Symbol	MLANA
Entrez Gene	2315
Alt Symbol	MART-1, MART1
Species	Human
Gene Type	protein-coding
Description	melan-A
Other Description	antigen LB39-AA|antigen SK29-AA|melanoma antigen recognized by T-cells 1|protein Melan-A
Swissprots	Q6ICU4 Q16655
Accessions	CAC37866 CAD79827 EAW58755 EAW58756 Q16655 AK312149 BAG35083 BC014423 AAH14423 CR450299 CAG29295 DQ892257 ABM83183 DQ895459 ABM86385 U06452 AAA19238 U06654 AAA20389 NM_005511 NP_005502
Function	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. {ECO:0000269|PubMed:15695812, ECO:0000269|PubMed:19717472}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
Tissue Specificity	Expression is restricted to melanoma and melanocyte cell lines and retina.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MelanA full length protein - ab114312 from Abcam Category Protein Source Wheat germ Species Human

Human MelanA protein fragment - ab157272 from Abcam Category Protein Source E. coli Species Human

MLANA / Melan-A Antibody Blocking Peptide - LS-E1156 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Melan-A/MART-1 Recombinant Protein - H00002315-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Melan-A/MART-1 Protein - NBP2-23223 from Novus Biologicals Category Protein Prices $299.00 Sizes 100 µg Source E.coli Species Human

Melan-A/MART-1 Protein - NBP1-99440 from Novus Biologicals Category Protein Species Human

Recombinant Human Melan-A/MART-1 Protein - NBP1-99757 from Novus Biologicals Category Protein Prices $695.00 Sizes 50 µg Source E. coli Species Human

MART-1Melan-A-Antibody-Center-Blocking-peptide - BP11689c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Melan A recombinant protein - GTX65094 from GeneTex Category Protein Prices $4,949.00 Sizes 1 mg Source E. coli Species Human

Melan A recombinant protein - GTX65095 from GeneTex Category Protein Prices $689.00 Sizes 50 μg Source E. coli Species Human

Human MLANA protein - orb246558 from Biorbyt Category Protein Prices $213.00, $408.00, $612.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

Human MLANA protein - orb191241 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli Species Human

Human MLANA protein - orb246852 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

MART1 peptide - orb72961 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

Human MART1 (26-35) peptide - orb70846 from Biorbyt Category Peptide Prices $357.00 Sizes 5 mg Species Human

MART1 protein - 30R-2721 from Fitzgerald Category Protein Prices $275.00 Sizes 5 µg Source E.coli Species Human

MLANA protein (His tag) - 80R-2851 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

MART-1 (27-35) Peptide - abx064601 from Abbexa Category Peptide Source Human Species Human

MART-1 Blocking Peptide - abx062627 from Abbexa Category Peptide Species Human

MART-1 (48-118, His-tag) - AR50970PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

MART-1 (48-118, His-tag) - AR50970PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

MART-1 - H00002315-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MART-1 - H00002315-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MLANA, 48-118aa, Human, His tag, E.coli - 01-P2146 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

MLANA fusion protein - Ag13346 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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