PAAF1

Gene Symbol	PAAF1
Entrez Gene	80227
Alt Symbol	PAAF, Rpn14, WDR71
Species	Human
Gene Type	protein-coding
Description	proteasomal ATPase-associated factor 1
Other Description	WD repeat domain 71|WD repeat-containing protein 71
Swissprots	Q7Z500 Q53HS9 B7ZAS9 Q8TBU6 Q4G165 B4DPB0 A6NDR5 Q9BRP4 Q9HAB6
Accessions	EAW74917 EAW74918 EAW74919 Q9BRP4 AF087895 AAP97194 AK021910 BAB13933 AK222501 BAD96221 AK225520 AK298258 BAG60522 AK309133 AK316394 BAH14765 BC006142 AAH06142 BC021541 AAH21541 BC028628 AAH28628 BC028677 BC045774 CD243380 DC354686 HQ448172 ADQ32653 XM_005274308 XP_005274365 XM_005274309 XP_005274366 XM_005274310 XP_005274367 XM_011545272 XP_011543574 XM_011545273 XP_011543575 XR_950069 NM_001267803 NP_001254732 NM_001267804 NP_001254733 NM_001267805 NP_001254734 NM_001267806 NP_001254735 NM_025155 NP_079431
Function	Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation. {ECO:0000269|PubMed:15831487, ECO:0000269|PubMed:17289585, ECO:0000269|PubMed:22316138}.
Tissue Specificity	Ubiquitously expressed, with highest levels in kidney, brain and testis. {ECO:0000269|PubMed:15831487}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAAF1 protein (His-DHFR tag) - ab127773 from Abcam Category Protein Source E. coli Species Human

PAAF1 Antibody Blocking Peptide - LS-E7718 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAAF1 Antibody Blocking Peptide - LS-E24256 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAAF1 Recombinant Protein - H00080227-P01 from Novus Biologicals Category Protein

PAAF1-Antibody-N-term-Blocking-Peptide - BP5062a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PAAF1 - H00080227-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

PAAF1 fusion protein - ag11880 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

PAAF1 fusion protein - ag11892 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Proteasomal ATPase-associated factor 1(PAAF1) - CSB-YP017351HU CSB-EP017351HU CSB-BP017351HU CSB-MP017351HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PAAF1 - TP302994 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Proteasomal ATPase-associated factor 1 (PAAF1), Recombinant Protein - MBS1409924 from MyBioSource Category Protein Prices $1,160.00, $1,160.00, $1,390.00, $1,390.00, $1,860.00, $1,860.00, $2,325.00, $2,325.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PAAF1 Recombinant Protein Antigen - NBP1-82310PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PAAF1 Peptide, Human - M34GP11220H from Creative Peptides Category Peptide Source Synthetic. Species Human

PAAF1 Recombinant Protein Antigen - NBP2-55195PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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