PAAF1

Gene Symbol PAAF1
Entrez Gene 80227
Alt Symbol PAAF, Rpn14, WDR71
Species Human
Gene Type protein-coding
Description proteasomal ATPase-associated factor 1
Other Description WD repeat domain 71|WD repeat-containing protein 71
Swissprots Q7Z500 Q53HS9 B7ZAS9 Q8TBU6 Q4G165 B4DPB0 A6NDR5 Q9BRP4 Q9HAB6
Accessions EAW74917 EAW74918 EAW74919 Q9BRP4 AF087895 AAP97194 AK021910 BAB13933 AK222501 BAD96221 AK225520 AK298258 BAG60522 AK309133 AK316394 BAH14765 BC006142 AAH06142 BC021541 AAH21541 BC028628 AAH28628 BC028677 BC045774 CD243380 DC354686 HQ448172 ADQ32653 XM_005274308 XP_005274365 XM_005274309 XP_005274366 XM_005274310 XP_005274367 XM_011545272 XP_011543574 XM_011545273 XP_011543575 XR_950069 NM_001267803 NP_001254732 NM_001267804 NP_001254733 NM_001267805 NP_001254734 NM_001267806 NP_001254735 NM_025155 NP_079431
Function Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation. {ECO:0000269|PubMed:15831487, ECO:0000269|PubMed:17289585, ECO:0000269|PubMed:22316138}.
Tissue Specificity Ubiquitously expressed, with highest levels in kidney, brain and testis. {ECO:0000269|PubMed:15831487}.

PAAF1 CRISPR/Cas9 KO Plasmid (h) - sc-413366 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAAF1 HDR Plasmid (h) - sc-413366-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAAF1 Double Nickase Plasmid (h) - sc-413366-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAAF1 Double Nickase Plasmid (h2) - sc-413366-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAAF1 CRISPR Activation Plasmid (h) - sc-413366-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAAF1 CRISPR Activation Plasmid (h2) - sc-413366-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAAF1 Lentiviral Activation Particles (h) - sc-413366-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAAF1 Lentiviral Activation Particles (h2) - sc-413366-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAAF1 siRNA (h) - sc-96876 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAAF1 shRNA Plasmid (h) - sc-96876-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAAF1 shRNA (h) Lentiviral Particles - sc-96876-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU057501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16245 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16245 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03066 from Sigma-Aldrich

Category miRNA

PAAF1 siRNA (Human) - CRJ2815 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PAAF1 (NM_025155.2) - SHH369716 from Creative biogene

Category siRNA
Species Reactivities Human

Human PAAF1 siRNA - orb273316 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PAAF1 shRNA Plasmid (Human) - CHJ2815 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PAAF1 miRNA 3'UTR clone - MiUTR3H-13548 from Creative biogene

Species Reactivities Human
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