Gene Symbol | CARD17 |
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Entrez Gene | 440068 |
Alt Symbol | INCA |
Species | Human |
Gene Type | protein-coding |
Description | caspase recruitment domain family, member 17 |
Other Description | Inhibitory CARD|caspase recruitment domain-containing protein 17|caspase-1 inhibitor INCA|inhibitory caspase recruitment domain (CARD) protein|inhibitory caspase recruitment domain protein |
Swissprots | Q5XLA6 |
Accessions | EAW67064 Q5XLA6 AY761064 AAV28630 BC146363 AAI46364 XM_011542838 XP_011541140 NM_001007232 NP_001007233 |
Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. {ECO:0000269|PubMed:15383541}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15383541}. |
Anti-INCA antibody - ab99280 from Abcam
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Anti-INCA antibody - ab67377 from Abcam
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Anti-INCA antibody - ab113892 from Abcam
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Anti-INCA antibody - C-terminal - ab199183 from Abcam
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Anti-CARD17 / INCA Antibody - LS-C306738 from LifeSpan Bioscience
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Anti-CARD17 / INCA Antibody - LS-C308488 from LifeSpan Bioscience
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Anti-CARD17 / INCA Antibody (aa51-100) - LS-C135943 from LifeSpan Bioscience
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Anti-CARD17 / INCA Antibody (aa97-110) - LS-C108939 from LifeSpan Bioscience
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INCA Antibody - NBP1-46144 from Novus Biologicals
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INCA Antibody - NBP1-74090 from Novus Biologicals
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INCA Antibody - H00440068-B01 from Novus Biologicals
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INCA Antibody - H00440068-B01P from Novus Biologicals
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INCA Antibody (1G6) - H00440068-M01 from Novus Biologicals
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INCA Antibody (1G6) - H00440068-M01A from Novus Biologicals
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CARD17 Polyclonal Antibody - bs-7090R from Bioss
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Anti-INCA antibody produced in mouse - SAB1408535 from Sigma-Aldrich
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Monoclonal Anti-CARD17 antibody produced in mouse - SAB1403509 from Sigma-Aldrich
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Anti-CASP1 antibody produced in rabbit - HPA003056 from Sigma-Aldrich
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CARD17 antibody - middle region (ARP61219_P050) - ARP61219_P050 from Aviva Systems Biology
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INCA-Antibody - AF2223a from Abgent, a WuXi AppTec company
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INCA antibody, C-term - GTX47540 from GeneTex
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Anti -CARD17 (Caspase Recruitment Domain Family, Member 17, INCA, Inhibitory CaspaseRecruitment Domain Protein) - C1340-08 from USBiological Life Science
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Anti -CARD17 (Caspase Recruitment Domain Family, Member 17, INCA, Inhibitory CaspaseRecruitment Domain Protein) - 124340 from USBiological Life Science
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Anti -CARD17 (Caspase Recruitment Domain Family, Member 17, INCA, Inhibitory CaspaseRecruitment Domain Protein) (AP) - C1340-08-AP from USBiological Life Science
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Anti -CARD17 (Caspase Recruitment Domain Family, Member 17, INCA, Inhibitory CaspaseRecruitment Domain Protein) (APC) - C1340-08-APC from USBiological Life Science
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