Gene Symbol | GLDC |
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Entrez Gene | 2731 |
Alt Symbol | GCE, GCSP, HYGN1 |
Species | Human |
Gene Type | protein-coding |
Description | glycine dehydrogenase (decarboxylating) |
Other Description | glycine cleavage system protein P|glycine decarboxylase P-protein|glycine dehydrogenase (aminomethyl-transferring)|glycine dehydrogenase (decarboxylating), mitochondrial|glycine dehydrogenase [decarboxylating], mitochondrial |
Swissprots | Q2M2F8 P23378 |
Accessions | AAK28443 EAW58739 EAW58740 P23378 AI480362 AK308470 AK310534 AK314156 BAG36841 AW593954 BC111993 AAI11994 BC111995 AAI11996 D90239 BAA14286 DA741442 DR002916 M63635 AAA36478 M64590 AAA36463 NM_000170 NP_000161 |
Function | The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH). |
Subcellular Location | Mitochondrion. |
Top Pathways | Glycine, serine and threonine metabolism, Carbon metabolism |
GLDC Antibody - 12794 from Cell Signaling Technology
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GLDC (H-9) - sc-376196 from Santa Cruz Biotechnology
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GLDC (A-9) - sc-376106 from Santa Cruz Biotechnology
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GLDC (T-14) - sc-162874 from Santa Cruz Biotechnology
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GLDC (H-300) - sc-134707 from Santa Cruz Biotechnology
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GLDC (I-14) - sc-162872 from Santa Cruz Biotechnology
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Anti-GLDC antibody - ab97625 from Abcam
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Anti-GLDC Antibody (aa49-77, AP) - LS-C214712 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa49-77, Biotin) - LS-C214715 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa49-77, APC) - LS-C214714 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa49-77, FITC) - LS-C214716 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa49-77, Azide-free, HRP) - LS-C214717 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa49-77, PE) - LS-C214718 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa627-833, Biotin) - LS-C299236 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa627-833, Biotin) - LS-C299837 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa81-268, FITC) - LS-C301384 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa627-833, FITC) - LS-C302187 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa56-85) - LS-C321648 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa49-77) - LS-C166500 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa81-268) - LS-C294281 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa627-833) - LS-C294280 from LifeSpan Bioscience
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Anti-GLDC Antibody (aa442-723) - LS-C186145 from LifeSpan Bioscience
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GLDC Antibody - NBP1-32907 from Novus Biologicals
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GLDC Antibody - NBP2-38682 from Novus Biologicals
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GLDC Antibody - NBP1-83374 from Novus Biologicals
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