ERN2

Gene Symbol ERN2
Entrez Gene 10595
Alt Symbol IRE1-BETA, IRE1b
Species Human
Gene Type protein-coding
Description endoplasmic reticulum to nucleus signaling 2
Other Description ER to nucleus signalling 2|IRE1 beta|IRE1, S. cerevisiae, homolog of|endoplasmic reticulum to nucleus signalling 2|endoplasmic reticulum-to-nucleus signaling 2|hIRE2p|inositol-requiring 1 beta|inositol-requiring protein 2|serine/threonine-protein kinase/endoribonuclease IRE2
Swissprots Q76MJ5 Q6ZNC0
Accessions EAW55802 Q76MJ5 AB047079 BAB21297 AK131280 BAD18455 AK309313 AK310834 BC156238 AAI56239 BC157113 AAI57114 BU608100 EF560720 ABQ59030 EF560739 ABQ59049 GQ129249 ACT64383 GQ129250 ACT64384 XM_005255044 XP_005255101 XM_011545708 XP_011544010 XM_011545709 XP_011544011 XM_011545710 XP_011544012 XM_011545711 XP_011544013 XM_011545712 XP_011544014 XM_011545713 XP_011544015 XR_950727 NM_001308220 NP_001295149 NM_033266 NP_150296
Function Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. {ECO:0000269|PubMed:11175748}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:11175748}; Single-pass type I membrane protein {ECO:0000269|PubMed:11175748}.

IRE1β siRNA (h) - sc-40707 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRE1β shRNA Plasmid (h) - sc-40707-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRE1β shRNA (h) Lentiviral Particles - sc-40707-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU068011 from Sigma-Aldrich

Category siRNA

MISSION® siRNA - SIHK0741 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0743 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0742 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN7972 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7972 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04112 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04112

ERN2 siRNA (Human) - CRH7212 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERN2 RNAi - H00010595-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ERN2 - MBS8239855 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ERN2 (NM_033266.3) - SHH287193 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ERN2(NM_033266.3) - SHH039071 from Creative biogene

Category siRNA
Species Reactivities Human

ERN2 shRNA Plasmid (Human) - CHH7212 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ERN2 miRNA 3'UTR clone - MiUTR1H-03303 from Creative biogene

Species Reactivities Human
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