HRH2

Gene Symbol HRH2
Entrez Gene 3274
Alt Symbol H2R
Species Human
Gene Type protein-coding
Description histamine receptor H2
Other Description HH2R|gastric receptor 1|gastric receptor I|histamine H2 receptor
Swissprots Q14464 B5BUP7 Q7Z5R9 P25021
Accessions AAA58647 BAA08618 BAA84279 BAA94469 CAA66832 EAW61369 P25021 AB023487 AB451483 BAG70297 AY136744 AAN01270 BC054510 AAH54510 CF147823 XM_005265904 XP_005265961 XM_006714864 XP_006714927 XM_006714865 XP_006714928 XM_011534548 XP_011532850 XM_011534549 XP_011532851 XR_245274 NM_001131055 NP_001124527 NM_022304 NP_071640
Function The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Top Pathways Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction

Histamine H2 Receptor (M-19) - sc-33974 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Histamine H2 Receptor (M-19): sc-33974. Western blot analysis of Histamine H2 Receptor expression in COLO 320DM whole cell lysate. Note presence of proteolytic fragment.

Histamine H2 Receptor (H-70) - sc-50314 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Histamine H2 Receptor (A-20) - sc-19773 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Histamine H2 Receptor (A-20): sc-19773. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic staining of glandular cells.

Histamine H2 Receptor (S-20) - sc-33973 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Histamine H2 Receptor (S-20): sc-33973. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic staining of glandular cells.

Anti-HRH2 antibody - ab188933 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of Human stomach, parietal cells, tissue labeling HRH2 using ab188933 at 38 µg/ml.

Anti-HRH2 antibody - ab118279 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-HRH2 antibody (ab118279) at 0.1 µg/ml + Human Duodenum lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-HRH2 antibody - ab123873 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HRH2 antibody (ab123873) at 1/100 dilution + Human Uterus cell line lysate at 35 µg

Anti-HRH2 antibody - ab96590 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HRH2 antibody (ab96590) at 1/1000 dilution (10% SDS PAGE) + HeLa whole cell lysate at 30 µg

Anti-HRH2 antibody - ab134238 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HRH2 antibody (ab134238) at 1 µg/ml + Human fetal brain lysate at 10 µg

Anti-HRH2 antibody - ab121010 from Abcam

Prices $242.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-HRH2 antibody [EPR5630] - ab108540 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5630
All lanes : Anti-HRH2 antibody [EPR5630] (ab108540) at 1/10000 dilutionLane 1 : Human fetal brain lysateLane 2 : SH-SY5Y cell lysateLane 3 : Human adrenal gland lysateLysates/proteins at 10 µg per lane.

Anti-HRH2 / Histamine H2 Receptor Antibody (aa179-224) - LS-C313796 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HRH2 / Histamine H2 Receptor Antibody (aa189-218) - LS-C165016 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HRH2 Antibody western blot of Uterus tissue lysates (35 ug/lane). The HRH2 antibody detected the HRH2 protein (arrow).

Anti-HRH2 / Histamine H2 Receptor Antibody (aa308-321) - LS-C139809 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
HRH2 antibody (0.1 ug/ml) staining of Duodenum lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-HRH2 / Histamine H2 Receptor Antibody (aa1-45) - LS-C185950 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded H520 xenograft using Histamine H2 Receptor antibody at 1:100 dilution.

Anti-HRH2 / Histamine H2 Receptor Antibody (N-Terminus) - LS-C24231 from LifeSpan Bioscience

Prices $515.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-HRH2 / Histamine H2 Receptor Antibody (C-Terminus) - LS-C24232 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-HRH2 / Histamine H2 Receptor Antibody (aa335-349) - LS-C54969 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-HRH2 / Histamine H2 Receptor Antibody (aa309-323) - LS-C154855 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-HRH2 / Histamine H2 Receptor Antibody (aa131-180) - LS-C120730 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of LOVO cells, using HRH2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-HRH2 / Histamine H2 Receptor Antibody (aa188-218, AP) - LS-C258896 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HRH2 / Histamine H2 Receptor Antibody (C-Terminus) - LS-C152014 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HRH2 / Histamine H2 Receptor antibody Western Blot of Fetal Brain.

Anti-HRH2 / Histamine H2 Receptor Antibody (aa188-218, APC) - LS-C258897 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HRH2 / Histamine H2 Receptor Antibody (aa188-218, Biotin) - LS-C258898 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HRH2 / Histamine H2 Receptor Antibody (Internal, clone EPR5630) - LS-C138612 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5630
Western blot analysis on (A) fetal brain, (B) SH-SY5Y, and (C) human adrenal gland lysates using anti-Histamine H2 Receptor antibody.
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