HRH2

Gene Symbol HRH2
Entrez Gene 3274
Alt Symbol H2R
Species Human
Gene Type protein-coding
Description histamine receptor H2
Other Description HH2R|gastric receptor 1|gastric receptor I|histamine H2 receptor
Swissprots Q14464 B5BUP7 Q7Z5R9 P25021
Accessions AAA58647 BAA08618 BAA84279 BAA94469 CAA66832 EAW61369 P25021 AB023487 AB451483 BAG70297 AY136744 AAN01270 BC054510 AAH54510 CF147823 XM_005265904 XP_005265961 XM_006714864 XP_006714927 XM_006714865 XP_006714928 XM_011534548 XP_011532850 XM_011534549 XP_011532851 XR_245274 NM_001131055 NP_001124527 NM_022304 NP_071640
Function The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Top Pathways Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction

Histamine H2 Receptor CRISPR/Cas9 KO Plasmid (h) - sc-401935 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H2 Receptor HDR Plasmid (h) - sc-401935-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H2 Receptor Double Nickase Plasmid (h) - sc-401935-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H2 Receptor Double Nickase Plasmid (h2) - sc-401935-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H2 Receptor CRISPR Activation Plasmid (h) - sc-401935-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H2 Receptor CRISPR Activation Plasmid (h2) - sc-401935-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H2 Receptor Lentiviral Activation Particles (h) - sc-401935-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H2 Receptor Lentiviral Activation Particles (h2) - sc-401935-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histamine H2 Receptor siRNA (h) - sc-43837 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histamine H2 Receptor shRNA Plasmid (h) - sc-43837-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histamine H2 Receptor shRNA (h) Lentiviral Particles - sc-43837-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histamine H2 R RNAi - H00003274-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN10298 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10298 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00684 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00684

HRH2 siRNA (Human) - CRH2240 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HRH2 - MBS8218811 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HRH2 (NM_022304.2) - SHH314861 from Creative biogene

Category siRNA
Species Reactivities Human

HRH2 shRNA Plasmid (Human) - CHH2240 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HRH2 miRNA 3'UTR clone - MiUTR3H-01068 from Creative biogene

Species Reactivities Human

HRH2 miRNA 3'UTR clone - MiUTR3H-01069 from Creative biogene

Species Reactivities Human
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