Gene Symbol | HRH2 |
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Entrez Gene | 3274 |
Alt Symbol | H2R |
Species | Human |
Gene Type | protein-coding |
Description | histamine receptor H2 |
Other Description | HH2R|gastric receptor 1|gastric receptor I|histamine H2 receptor |
Swissprots | Q14464 B5BUP7 Q7Z5R9 P25021 |
Accessions | AAA58647 BAA08618 BAA84279 BAA94469 CAA66832 EAW61369 P25021 AB023487 AB451483 BAG70297 AY136744 AAN01270 BC054510 AAH54510 CF147823 XM_005265904 XP_005265961 XM_006714864 XP_006714927 XM_006714865 XP_006714928 XM_011534548 XP_011532850 XM_011534549 XP_011532851 XR_245274 NM_001131055 NP_001124527 NM_022304 NP_071640 |
Function | The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction |
Guinea pig HRH2 full length protein - ab90476 from Abcam
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HRH2 peptide (335-349) (Carboxyterminal end) - ab45807 from Abcam
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Human HRH2 full length protein - ab90481 from Abcam
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Rat HRH2 full length protein - ab90400 from Abcam
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HRH2 / Histamine H2 Receptor Antibody Blocking Peptide - LS-E3760 from LifeSpan Bioscience
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HRH2 / Histamine H2 Receptor Antibody Blocking Peptide - LS-E27727 from LifeSpan Bioscience
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HRH2 / Histamine H2 Receptor Antibody Blocking Peptide - LS-E27728 from LifeSpan Bioscience
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HRH2 / Histamine H2 Receptor Antibody Blocking Peptide - LS-E25939 from LifeSpan Bioscience
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HRH2 / Histamine H2 Receptor Antibody Blocking Peptide - LS-E28161 from LifeSpan Bioscience
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HRH2 / Histamine H2 Receptor Antibody Blocking Peptide - LS-E28160 from LifeSpan Bioscience
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HRH2 / Histamine H2 Receptor Antibody Blocking Peptide - LS-E23865 from LifeSpan Bioscience
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Histamine H2 R Blocking Peptide - NB600-812PEP from Novus Biologicals
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HRH2-Antibody-Center-Blocking-Peptide - BP14970c from Abgent, a WuXi AppTec company
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Histamine H2 Receptor blocking peptide - GTX89505-PEP from GeneTex
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Goat anti HRH2 antibody Immunizing peptide - orb17722 from Biorbyt
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Histamine H2 Receptor Blocking Peptide - abx062745 from Abbexa
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HRH2 Peptide - AC21-0768-P from Abcore
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HRH2 Peptide - AC21-2538-P from Abcore
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Histamine H2 receptor - H00003274-G01 from Acris Antibodies
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Histamine Receptor H2 Peptide - 45-733P from ProSci
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HRH2 Peptide - 42-385P from ProSci
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HRH2 fusion protein - ag4068 from Proteintech Group
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HRH2 fusion protein - ag16026 from Proteintech Group
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Recombinant Human HRH2 - HRH2-27612TH from Creative Biomart
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Recombinant Human HRH2 - HRH2-29324TH from Creative Biomart
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