COL8A2

Gene Symbol	COL8A2
Entrez Gene	1296
Alt Symbol	FECD, FECD1, PPCD, PPCD2
Species	Human
Gene Type	protein-coding
Description	collagen, type VIII, alpha 2
Other Description	collagen VIII, alpha-2 polypeptide|collagen alpha-2(VIII) chain|endothelial collagen
Swissprots	Q8TEJ5 Q5JV31 P25067
Accessions	AAA62822 AGN55423 AGN55424 AGN55425 AGN55426 AGN55427 AGN55428 AGN55429 AGN55430 EAX07388 P25067 AI084614 AK074129 BAB84955 AK090924 BC096295 AAH96295 BC096296 AAH96296 BC096297 AAH96297 BC099645 AAH99645 HY025990 XM_005270477 XP_005270534 NM_001294347 NP_001281276 NM_005202 NP_005193
Function	Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity). {ECO:0000250}.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane.
Tissue Specificity	Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve bundles in muscle, in the dura of the optic nerve, in cornea and sclera, and in the perichondrium of cartilaginous tissues. In the kidney, expressed in mesangial cells, glomerular endothelial cells, and tubular epithelial cells. Also expressed in mast cells, and in astrocytes during the repair process. Expressed in Descemet's membrane. {ECO:0000269|PubMed:10686422, ECO:0000269|PubMed:17888087}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human COL8A2 full length protein - ab158163 from Abcam Category Protein Source Wheat germ Species Human

Human COL8A2 protein fragment - ab158164 from Abcam Category Protein Source Wheat germ Species Human

COL8A2 / Collagen VIII Antibody Blocking Peptide - LS-E1269 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COL8A2 / Collagen VIII Antibody Blocking Peptide - LS-E21979 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COL8A2 / Collagen VIII Antibody Blocking Peptide - LS-E21978 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human COL8A2 Protein - H00001296-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human COL8A2 Protein - H00001296-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

COL8A2-Antibody-C-term-Blocking-peptide - BP11859b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

COL8A2 Blocking Peptide - 33R-3463 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

COL8A2 Blocking Peptide - 33R-1023 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human COL8a2 Protein - abx066017 from Abbexa Category Protein Source E.coli Species Human

Collagen type VIII alpha 2 chain - H00001296-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Collagen type VIII alpha 2 chain - H00001296-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Collagen type VIII alpha 2 chain - H00001296-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Collagen type VIII alpha 2 chain - H00001296-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Collagen Type VIII Alpha 2 (COL8a2), Human - 20-8688 from ARP American Research Products Category Protein Prices $479.00 Sizes 50 µg Source E.coli Species Human

COL8A2 fusion protein - ag17319 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Collagen Type VIII Alpha 2 (COL8a2) - RPD124Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Collagen Type VIII Alpha 2 (COL8a2) - RPD124Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Collagen Type VIII Alpha 2 (COL8a2) - RPD124Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Collagen alpha-2(VIII) chain(COL8A2) - CSB-YP005756HU CSB-EP005756HU CSB-BP005756HU CSB-MP005756HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Collagen type VIII alpha 2 chain - TP316003 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

COL8A2 Recombinant Protein Antigen - NBP2-13857PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

COL8A2 Peptide, Human - M34GP03471H from Creative Peptides Category Peptide Source Synthetic. Species Human

COL8A2 Recombinant Protein (OPCD02346) - OPCD02346 from Aviva Systems Biology Category Protein Source E.coli Species Human

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