COL8A2

Gene Symbol COL8A2
Entrez Gene 1296
Alt Symbol FECD, FECD1, PPCD, PPCD2
Species Human
Gene Type protein-coding
Description collagen, type VIII, alpha 2
Other Description collagen VIII, alpha-2 polypeptide|collagen alpha-2(VIII) chain|endothelial collagen
Swissprots Q8TEJ5 Q5JV31 P25067
Accessions AAA62822 AGN55423 AGN55424 AGN55425 AGN55426 AGN55427 AGN55428 AGN55429 AGN55430 EAX07388 P25067 AI084614 AK074129 BAB84955 AK090924 BC096295 AAH96295 BC096296 AAH96296 BC096297 AAH96297 BC099645 AAH99645 HY025990 XM_005270477 XP_005270534 NM_001294347 NP_001281276 NM_005202 NP_005193
Function Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity). {ECO:0000250}.
Subcellular Location Secreted, extracellular space, extracellular matrix, basement membrane.
Tissue Specificity Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve bundles in muscle, in the dura of the optic nerve, in cornea and sclera, and in the perichondrium of cartilaginous tissues. In the kidney, expressed in mesangial cells, glomerular endothelial cells, and tubular epithelial cells. Also expressed in mast cells, and in astrocytes during the repair process. Expressed in Descemet's membrane. {ECO:0000269|PubMed:10686422, ECO:0000269|PubMed:17888087}.

COL8A2 (G-20) - sc-82841 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

COL8A2 (N-16) - sc-82843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
COL8A2 (N-16): sc-82843. Western blot analysis of COL8A2 expression in HeLa (A), Jurkat (B), K-562 (C) and CCRF-CEM (D) whole cell lysates.

COL8A2 (H-45) - sc-134947 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

COL8A2 (P-15) - sc-82844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-COL8A2 antibody - ab111409 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-COL8A2 antibody (ab111409) at 1/100 dilution + CEM cell lysate at 35 µg

Anti-COL8A2 antibody - ab112110 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-COL8A2 antibody (ab112110) at 1 µg/ml + Human Fetal Liver lysate at 10 µg

Anti-COL8A2 / Collagen VIII Antibody (aa578-607, AP) - LS-C208540 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa578-607, Biotin) - LS-C208542 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa578-607, APC) - LS-C208541 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa578-607, Azide-free, HRP) - LS-C208544 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa578-607, PE) - LS-C208545 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa578-607, FITC) - LS-C208543 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa537-703, Biotin) - LS-C299754 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (clone 1F4) - LS-C196947 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F4
COL8A2 monoclonal antibody (M01), clone 1F4. Western Blot analysis of COL8A2 expression in K-562.

Anti-COL8A2 / Collagen VIII Antibody (aa469-518) - LS-C135697 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
COL8A2 antibody LS-C135697 Western blot of A549 cell lysate.

Anti-COL8A2 / Collagen VIII Antibody (aa537-703, FITC) - LS-C303172 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa533-698, Biotin) - LS-C299756 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa578-607) - LS-C329411 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa533-698, FITC) - LS-C303174 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COL8A2 / Collagen VIII Antibody (aa285-334) - LS-C135494 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
COL8A2 antibody LS-C135494 Western blot of Fetal Liver lysate.

Anti-COL8A2 / Collagen VIII Antibody (aa533-698) - LS-C293440 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant COL8A2 / Collagen VIII.

Anti-COL8A2 / Collagen VIII Antibody (aa537-703) - LS-C294084 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant COL8A2 / Collagen VIII.

Anti-COL8A2 / Collagen VIII Antibody (aa578-607) - LS-C166931 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
COL8A2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

COL8A2 Antibody - NBP2-30020 from Novus Biologicals

Prices $299.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western Blot: COL8A2 Antibody [NBP2-30020] - Western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the COL8A2 antibody detected the COL8A2 protein (arrow).

COL8A2 Antibody - NBP1-79787 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: COL8A2 Antibody [NBP1-79787] - Human Liver cell lysate, concentration 0.2-1 ug/ml.
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