EPHB3

Gene Symbol	EPHB3
Entrez Gene	2049
Alt Symbol	ETK2, HEK2, TYRO6
Species	Human
Gene Type	protein-coding
Description	EPH receptor B3
Other Description	EK2|EPH-like kinase 2|EPH-like tyrosine kinase 2|EPH-like tyrosine kinase-2|embryonic kinase 2|ephrin type-B receptor 3|human embryo kinase 2|tyrosine-protein kinase TYRO6
Swissprots	Q7Z740 P54753
Accessions	CAT16951 EAW78236 EAW78237 P54753 BC052968 AAH52968 CB993133 X75208 CAA53021 NM_004443 NP_004434
Function	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis,
Subcellular Location	Cell membrane {ECO:0000269|PubMed:15536074}; Single-pass type I membrane protein {ECO:0000269|PubMed:15536074}. Cell projection, dendrite {ECO:0000250}.
Tissue Specificity	Ubiquitous.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EphB3 (A-12) - sc-514139 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

EphB3 (H-85) - sc-28981 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

EphB3 (E-20) - sc-27111 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

EphB3 (L-19) - sc-9318 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

EphB3 (S-16) - sc-27110 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

EphB3 (7E5) - sc-100299 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-Eph receptor B3 (phospho Y608) antibody - ab191502 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Eph receptor B3 antibody - ab10617 from Abcam Prices $373.00 Sizes 25 µg Host Goat Clonality Polyclonal

Anti-Eph receptor B3 antibody - ab95224 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Eph receptor B3 antibody - ab106295 from Abcam Prices $370.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-Eph receptor B3 antibody - ab133879 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Eph receptor B3 antibody [EPR8280] - ab133742 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR8280

Anti-Eph receptor B3 antibody - N-terminal - ab135809 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (aa30-554) - LS-C125537 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-EPHB3 / EPH Receptor B3 Antibody - LS-C109412 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (N-Terminus) - LS-C144693 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (aa38-550) - LS-C184226 from LifeSpan Bioscience Prices $605.00 Sizes 100 µg Host Sheep Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (N-Terminus, AP) - LS-C225414 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (N-Terminus, Biotin) - LS-C225416 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (N-Terminus, APC) - LS-C225415 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (N-Terminus, FITC) - LS-C225417 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (clone 1E12) - LS-C104944 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1E12

Anti-EPHB3 / EPH Receptor B3 Antibody (N-Terminus, Azide-free, HRP) - LS-C225418 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (aa552-601) IHC-plus™ - LS-B8266 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-EPHB3 / EPH Receptor B3 Antibody (aa29-59) - LS-C100285 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Search more