EPHB3

Gene Symbol	EPHB3
Entrez Gene	2049
Alt Symbol	ETK2, HEK2, TYRO6
Species	Human
Gene Type	protein-coding
Description	EPH receptor B3
Other Description	EK2|EPH-like kinase 2|EPH-like tyrosine kinase 2|EPH-like tyrosine kinase-2|embryonic kinase 2|ephrin type-B receptor 3|human embryo kinase 2|tyrosine-protein kinase TYRO6
Swissprots	Q7Z740 P54753
Accessions	CAT16951 EAW78236 EAW78237 P54753 BC052968 AAH52968 CB993133 X75208 CAA53021 NM_004443 NP_004434
Function	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis,
Subcellular Location	Cell membrane {ECO:0000269|PubMed:15536074}; Single-pass type I membrane protein {ECO:0000269|PubMed:15536074}. Cell projection, dendrite {ECO:0000250}.
Tissue Specificity	Ubiquitous.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HTScan® EphB3 Kinase Assay Kit - 7716 from Cell Signaling Technology Category Assay Kit

Mouse EPHB3 / EPH Receptor B3 ELISA Kit (Sandwich ELISA) - LS-F7554 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.051 ng/ml Range 0.156-10 ng/ml

Rat EPHB3 / EPH Receptor B3 ELISA Kit (Sandwich ELISA) - LS-F7709 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.067 ng/ml Range 0.156-10 ng/ml

Phosphotyrosine EPHB3 / Ephrin Type-B Receptor 3 ELISA Kit - RAB0951 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Ephrin type-B receptor 3 (EPHB3), Human, ELISA Kit - CSB-EL007731HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

EPHB3 (Human) IP-WB Antibody Pair - H00002049-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

EPH receptor B3, ELISA Kit - MBS919680 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.039 ng /ml. Range 0.156 ng/ml -10 ng/ml.

Ephrin Type B Receptor 3 (EPHB3), ELISA Kit - MBS2022936 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.067ng/mL. Range 0.156-10ng/mL

Ephrin Type B Receptor 3 (EPHB3), ELISA Kit - MBS2019649 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.051ng/mL. Range 0.156-10ng/mL

ELISA Kit for Ephrin Type B Receptor 3 (EPHB3) - SEE118Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.051ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Ephrin Type B Receptor 3 (EPHB3) - SEE118Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.067ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Ephrin type-B receptor 3(EPHB3) ELISA kit - CSB-EL007731HU from Cusabio Category ELISA Kit Sensitivity 0.039ng/ml Range 0.156 ng/ml-10 ng/ml

Custom Human EphB3 ELISA - ELH-EPHB3 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human EphB3 ELISA - RAB1440 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Human Ephrin type-B receptor 3 (EPHB3) ELISA Kit - EKC33588 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Custom Human EphB3 ELISA - ELH-EPHB3-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human/Mouse Phosphotyrosine EphB3 ELISA - PEL-EphB3-Y-1 from RayBiotech Category ELISA Kit Prices $398.00, $716.40, $1,592.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human EPHB3 ELISA Kit - E013302 from Biobool Category ELISA Kit Sensitivity 0.039 ng /ml.

EPHB3 ELISA Kit (Human) (OKCA01226) - OKCA01226 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 0.039 ng/mL Range 0.156 - 10 ng/mL

Ephrin Type B Receptor 3 (EPHB3), ELISA Kit - MBS9376858 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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