ENTPD4

Gene Symbol	ENTPD4
Entrez Gene	9583
Alt Symbol	LALP70, LAP70, LYSAL1, NTPDase-4, UDPase
Species	Human
Gene Type	protein-coding
Description	ectonucleoside triphosphate diphosphohydrolase 4
Other Description	golgi luminal UDPase|guanosine-diphosphatase like protein|lysosomal apyrase-like 1|lysosomal apyrase-like protein of 70 kDa|uridine-diphosphatase
Swissprots	O15092 D3DSS3 Q9Y227
Accessions	CAB45655 EAW63621 EAW63622 EAW63623 Q9Y227 AB002390 BAA21575 AF016032 AAC17217 AJ131358 CAB40415 AK300464 BAG62183 BC034477 AAH34477 CN313713 CN313716 DB091432 DB153397 DC341200 DQ890824 ABM81750 DQ893978 ABM84904 NM_001128930 NP_001122402 NM_004901 NP_004892
Function	Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.
Subcellular Location	Golgi apparatus membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Localizes in the Golgi and autophagic vacuoles/lysosomes.
Tissue Specificity	Ubiquitous. Highest expression in testis and lowest in bladder.
Top Pathways	Lysosome, Purine metabolism, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ENTPD4 protein fragment - ab127104 from Abcam Category Protein Source E. coli Species Human

ENTPD4 / LALP70 Antibody Blocking Peptide - LS-E5653 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ENTPD4 Protein - H00009583-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

ENTPD4 Partial Recombinant Protein - H00009583-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ENTPD4-Antibody-N-term-Blocking-Peptide - BP18180a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ENTPD4 - H00009583-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

ENTPD4 - H00009583-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ENTPD4 - H00009583-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ENTPD4 fusion protein - Ag5175 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

ENTPD4 fusion protein - Ag4986 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ENTPD4, His-tagged - ENTPD4-12469H from Creative Biomart Category Protein Source E.coli Species Human

ENTPD4 (transcript variant 1) - TP314422 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ENTPD4 Recombinant Protein Antigen - NBP1-81510PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ENTPD4 Peptide, Human - M34GP04958H from Creative Peptides Category Peptide Source Synthetic. Species Human

Ectonucleoside triphosphate diphosphohydrolase 4 (ENTPD4), Recombinant Protein - MBS7014267 from MyBioSource Category Protein Prices $1,410.00, $2,395.00, $3,600.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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