KISS1

Gene Symbol	KISS1
Entrez Gene	3814
Alt Symbol	HH13, KiSS-1
Species	Human
Gene Type	protein-coding
Description	KiSS-1 metastasis-suppressor
Other Description	kisspeptin-1|malignant melanoma metastasis-suppressor|metastasis-suppressor KiSS-1|metastin|prepro-kisspeptin
Swissprots	A8K6N0 Q9HBP1 Q15726
Accessions	CBH19336 EAW91506 EAW91507 Q15726 AF218017 AAG17259 AK291695 BAF84384 AY117143 AAM78592 BC022819 AAH22819 DQ892799 ABM83725 DQ896046 ABM87045 U43527 AAC79512 XM_011509525 XP_011507827 NM_002256 NP_002247
Function	Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine- tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis a
Subcellular Location	Secreted.
Tissue Specificity	Very high expression in placenta, with the next highest level in testis and moderate levels in pancreas, liver, small intestine and brain at much lower levels. Expression levels increased in both early placentas and molar pregnancies and are reduced in choriocarcinoma cells. Expressed at higher levels in first trimester trophoblasts than at term of gestation, but only expressed in the villous trophoblast. {ECO:0000269|PubMed:11385580, ECO:0000269|PubMed:12414911, ECO:0000269|PubMed:15020672}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat KISS1 / Kisspeptin / Metastin ELISA Kit (Competitive EIA) - LS-F6545 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 9.35 pg/ml Range 24.69-2000 pg/ml

Human KISS1 / Kisspeptin / Metastin ELISA Kit (Sandwich ELISA) - LS-F8231 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 13.8 pg/ml Range 24.69-2000 pg/ml

Mouse KISS1 / Kisspeptin / Metastin ELISA Kit (Competitive EIA) - LS-F8897 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 12.35 pg/ml Range 24.69-2000 pg/ml

Rat KISS1 / Kisspeptin / Metastin ELISA Kit (Sandwich ELISA) - LS-F11877 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 24.69-2000 pg/ml

Mouse KISS1 / Kisspeptin / Metastin ELISA Kit (Sandwich ELISA) - LS-F11879 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 24.69-2000 pg/ml

Human KISS1 / Kisspeptin / Metastin ELISA Kit (Sandwich ELISA) - LS-F11878 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 24.69-2000 pg/ml

Kisspeptin 1 (KISS1), Human, ELISA Kit - SEC559Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 12.9pg/mL Range 31.2-2,000pg/mL

Metastasis-suppressor KiSS-1 (KISS1), Human, ELISA Kit - CSB-EL012373HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Metastasis-suppressor KiSS-1, KISS1, Human, ELISA Kit - E2063h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

KISS1 (Human) Matched Antibody Pair - H00003814-AP42 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

KiSS-1 metastasis-suppressor, ELISA Kit - MBS933835 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.078 ng/ml. Range 0.312 ng/ml -20 ng/ml.

KISS1, ELISA Kit - MBS2516124 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 75pg/mL Range 125-8000pg/mL

ELISA Kit for Kisspeptin 1 (KISS1) - SEC559Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 13.4pg/mL. Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA’s were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

Human Metastasis-suppressor KiSS-1(KISS1) ELISA kit - CSB-EL012373HU from Cusabio Category ELISA Kit Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

ELISA Kit for Kisspeptin 1 (KISS1) - SEC559Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 13.4pg/mL. Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA's were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

Human NPTX1(Neuronal Pentraxin 1) ELISA Kit - E-EL-H2129 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 75 pg/mLpg/mL Range 125~8000 pg/mL

Human Metastasis-suppressor KiSS-1 ELISA Kit - abx251409 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human KISS1 / Kisspeptin / Metastin ELISA Kit (Sandwich ELISA) - LS-F24240 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 75 pg/ml Range 24.69-2000 pg/ml

Human KISS1 / Kisspeptin / Metastin ELISA Kit (Sandwich ELISA) - LS-F23485 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 18.75 pg/ml Range 31.25 - 2000 pg/ml

Kisspeptin 1 (KISS1), Human, ELISA Kit - DL-KISS1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 31.2-2,000 pg/mL

Human KISS1(Kisspeptin 1) ELISA Kit - E-EL-H2129 from Elabscience Category ELISA Kit Sensitivity 75.00 pg/mL Range 125.00—8000 pg/mL

Kisspeptin 1, KISS1, Human, ELISA Kit - E-EL-H2129 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 75 Range 125-8000pg/mL

Human KISS1 ELISA Kit - abx575677 from Abbexa Category ELISA Kit Sensitivity 12.9 pg/ml Range 31.25 pg/ml - 2000 pg/ml

Human Metastasis-suppressor KiSS-1 (KISS1) ELISA Kit - EKC34597 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Human Metastasis-suppressor KiSS-1 ELISA Kit - EKE54095 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.078 ng/mL Range 0.156-10 ng/mL

Search more