AIMP2

Gene Symbol AIMP2
Entrez Gene 7965
Alt Symbol JTV-1, JTV1, P38, PRO0992
Species Human
Gene Type protein-coding
Description aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Other Description ARS-interacting multi-functional protein 2|aminoacyl tRNA synthase complex-interacting multifunctional protein 2|multisynthase complex auxiliary component p38|multisynthetase complex auxiliary component p38|protein JTV-1
Swissprots Q13155 Q96CZ5 Q75MR1 Q9P1L2
Accessions AAS00389 EAL23713 EAW55053 EAW55054 Q13155 AF116615 AAF71039 AK313037 BAG35870 BC002853 AAH02853 BC010156 AAH10156 BC013630 AAH13630 U24169 AAC50391 XM_005249847 XP_005249904 XM_005249848 XP_005249905 XM_005249850 XP_005249907 XM_006715772 XP_006715835 XM_011515519 XP_011513821 NM_006303 NP_006294
Function Required for assembly and stability of the aminoacyl- tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down- regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. {ECO:0000269|PubMed:16135753}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Note=Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus. {ECO:0000250}.

JTV1 (S-14) - sc-160455 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
JTV1 (S-14): sc-160455. Western blot analysis of JTV1 expression in COLO 320DM whole cell lysate.

JTV1 (N-15) - sc-160454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
JTV1 (N-15): sc-160454. Western blot analysis of JTV1 expression in K-562 whole cell lysate.

Anti-AIMP2/p38 antibody - ab101840 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-AIMP2/p38 antibody (ab101840) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-AIMP2/p38 antibody - ab125218 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AIMP2/p38 antibody (ab125218) at 1 µg/mlLane 1 : Rat liver tissue lysateLane 2 : Rat lung tissue lysateLane 3 : Rat kidney tissue lysateLane 4 : Rat brain tissue lysateLane 5 : Rabbit IgG (55kDa)Lane 6 : Jurkat whole cell lysateLane 7 : CEM whole cell lysateLane 8 : HUT whole cell lysateLane 9 : U93T whole cell lysate

Anti-AIMP2/p38 antibody - ab180897 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AIMP2/p38 antibody (ab180897) at 1 µg/mlLane 1 : HeLa cell lysateLane 2 : HeLa cell lysate with blocking peptideLysates/proteins at 15 µg per lane.

Anti-AIMP2/p38 antibody - ab31542 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-AIMP2/p38 antibody - ab82387 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AIMP2/p38 antibody (ab82387) at 1/50 dilution + NCI-H460 cell line lysates at 35 µg

Anti-AIMP2/p38 antibody - ab67471 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-AIMP2/p38 antibody (ab67471) at 1/500 dilutionLane 1 : AIMP2/p38 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-AIMP2 Antibody (aa298-320) - LS-C312637 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
AIMP2 antibody. IHC(P): Human Rectal Cancer Tissue.

Anti-AIMP2 Antibody - LS-C308567 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AIMP2 Antibody (aa151-200) - LS-C116836 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AIMP2 antibody LS-C116836 Western blot of HepG2 cell lysate.

Anti-AIMP2 Antibody (aa51-100) - LS-C116837 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AIMP2 antibody LS-C116837 Western blot of MCF7 cell lysate.

Anti-AIMP2 Antibody (clone 8E7) - LS-C198514 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8E7
JTV1 monoclonal antibody (M02), clone 8E7. Western Blot analysis of JTV1 expression in K-562.

Anti-AIMP2 Antibody (aa156-184) - LS-C97361 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of JTV1 (arrow) using rabbit polyclonal JTV1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the JTV1 gene.

Anti-AIMP2 Antibody (Internal) - LS-C201145 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of AIMP2 in rat small intestine tissue with AIMP2 antibody at 5 ug/ml.

p38 Antibody (8G4D11) - NBP2-37378 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8G4D11

p38 Antibody (10B11C8) - NBP2-37312 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10B11C8
Western Blot: p38 Antibody (10B11C8) [NBP2-37312] - Western blot analysis using MAPK14 mouse mAb against Hela (1), HEK293 (2), A431 (3), MCF-7 (4), RAW264.7 (5), Cos7 (6), C6 (7), Jurkat (8) and NIH/3T3 (9) cell lysate.

AIMP2 Antibody - NBP2-27094 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: AIMP2 Antibody [NBP2-27094] - Analysis of AIMP2 using AIMP2 antibody. Human spleen tissue lysate in the 1) absence and 2) presence of immunizing peptide probed with 2 ug/ml of AIMP2 antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

AIMP2 Antibody - NBP1-81575 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: AIMP2 Antibody [NBP1-81575] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

p38 Antibody - NB100-92248 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: p38 Antibody [NB100-92248] - Extracts from Jurkat cells.

AIMP2 Antibody - NBP2-15315 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: AIMP2 Antibody [NBP2-15315] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE; antibody diluted at 1:1000.

p38 Antibody - NBP1-51458 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: p38 [p Tyr182] Antibody [NBP1-51458] - p38 (Y182) pAb in extracts from PC12 cells.

p38 Antibody - NBP1-19821 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: p38 Antibody [NBP1-19821] - extracts from K562 cells.

AIMP2 Antibody - H00007965-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: AIMP2 Antibody [H00007965-B01P] - Analysis of JTV1 expression in transfected 293T cell line by JTV1 polyclonal antibody. Lane 1: JTV1 transfected lysate(35.2 KDa). Lane 2: Non-transfected lysate.

AIMP2 Antibody - NBP1-81574 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: AIMP2 Antibody [NBP1-81574] - Staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.
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