AIMP2

Gene Symbol AIMP2
Entrez Gene 7965
Alt Symbol JTV-1, JTV1, P38, PRO0992
Species Human
Gene Type protein-coding
Description aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Other Description ARS-interacting multi-functional protein 2|aminoacyl tRNA synthase complex-interacting multifunctional protein 2|multisynthase complex auxiliary component p38|multisynthetase complex auxiliary component p38|protein JTV-1
Swissprots Q13155 Q96CZ5 Q75MR1 Q9P1L2
Accessions AAS00389 EAL23713 EAW55053 EAW55054 Q13155 AF116615 AAF71039 AK313037 BAG35870 BC002853 AAH02853 BC010156 AAH10156 BC013630 AAH13630 U24169 AAC50391 XM_005249847 XP_005249904 XM_005249848 XP_005249905 XM_005249850 XP_005249907 XM_006715772 XP_006715835 XM_011515519 XP_011513821 NM_006303 NP_006294
Function Required for assembly and stability of the aminoacyl- tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down- regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. {ECO:0000269|PubMed:16135753}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Note=Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus. {ECO:0000250}.

JTV1 CRISPR/Cas9 KO Plasmid (h) - sc-406684 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JTV1 HDR Plasmid (h) - sc-406684-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JTV1 Double Nickase Plasmid (h) - sc-406684-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JTV1 Double Nickase Plasmid (h2) - sc-406684-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JTV1 CRISPR Activation Plasmid (h) - sc-406684-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JTV1 CRISPR Activation Plasmid (h2) - sc-406684-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JTV1 Lentiviral Activation Particles (h) - sc-406684-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JTV1 Lentiviral Activation Particles (h2) - sc-406684-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JTV1 siRNA (h) - sc-89346 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JTV1 shRNA Plasmid (h) - sc-89346-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JTV1 shRNA (h) Lentiviral Particles - sc-89346-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU000641 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2990 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2990 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00385 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00385

AIMP2 siRNA (Human) - CRH5326 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AIMP2 - MBS8239710 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AIMP2 (NM_006303.3) - SHH234014 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human JTV1(NM_006303.3) - SHG049057 from Creative biogene

Category siRNA
Species Reactivities Human

AIMP2 shRNA Plasmid (Human) - CHH5326 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AIMP2 miRNA 3'UTR clone - MiUTR1H-05079 from Creative biogene

Species Reactivities Human
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