AIMP2

Gene Symbol	AIMP2
Entrez Gene	7965
Alt Symbol	JTV-1, JTV1, P38, PRO0992
Species	Human
Gene Type	protein-coding
Description	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Other Description	ARS-interacting multi-functional protein 2|aminoacyl tRNA synthase complex-interacting multifunctional protein 2|multisynthase complex auxiliary component p38|multisynthetase complex auxiliary component p38|protein JTV-1
Swissprots	Q13155 Q96CZ5 Q75MR1 Q9P1L2
Accessions	AAS00389 EAL23713 EAW55053 EAW55054 Q13155 AF116615 AAF71039 AK313037 BAG35870 BC002853 AAH02853 BC010156 AAH10156 BC013630 AAH13630 U24169 AAC50391 XM_005249847 XP_005249904 XM_005249848 XP_005249905 XM_005249850 XP_005249907 XM_006715772 XP_006715835 XM_011515519 XP_011513821 NM_006303 NP_006294
Function	Required for assembly and stability of the aminoacyl- tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down- regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. {ECO:0000269|PubMed:16135753}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Note=Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AIMP2/p38 full length protein - ab152832 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

AIMP2 Antibody Blocking Peptide - LS-E21711 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AIMP2 Antibody Blocking Peptide - LS-E21712 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AIMP2 Antibody Blocking Peptide - LS-E7160 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human AIMP2 Protein - H00007965-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

AIMP2 Recombinant Protein - H00007965-P01 from Novus Biologicals Category Protein Species Human

JTV1-Antibody-Center-Blocking-Peptide - BP2861c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

p38 beta (Active) recombinant protein - GTX65220 from GeneTex Category Protein Prices $329.00 Sizes 5 μg Source Baculovirus (Sf9 insect cells) Species Human

SAPK4 (Active) recombinant protein - GTX65221 from GeneTex Category Protein Prices $329.00 Sizes 5 μg Source Baculovirus (Sf9 insect cells) Species Human

ERK2/MAPK1 blocking peptide - GTX89615-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

p38 alpha protein - 30R-2870 from Fitzgerald Category Protein Prices $425.00 Sizes 5 µg Source Sf-9 insect cells Species Human

p38 beta protein - 30R-2875 from Fitzgerald Category Protein Prices $425.00 Sizes 5 µg Source Sf-9 insect cells Species Human

P38 delta protein - 30R-2868 from Fitzgerald Category Protein Prices $425.00 Sizes 5 µg Source Sf-9 insect cells Species Human

p38 (phospho-Thr180) Blocking Peptide - abx062081 from Abbexa Category Peptide Species Human, Mouse, Rat, Dog, Zebrafish

p38 Blocking Peptide - abx062080 from Abbexa Category Peptide Species Human, Mouse, Rat, Dog, Zebrafish

JTV1 / AIMP2 - H00007965-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

JTV1 / AIMP2 - H00007965-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

JTV1 / AIMP2 - H00007965-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

JTV1 / AIMP2 - H00007965-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

AIMP2 Peptide - 7515P from ProSci Category Peptide Species Human

JTV1 fusion protein - ag0675 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

p38/JTV-1 Protein - 23-049-K from EMD Millipore Category Protein Species Human

p38/JTV-1 Protein, 10 µg - 23-049 from EMD Millipore Category Protein Prices $473.00 Sizes 10 µg

p38/JTV-1 Protein, 250 µg - 23-049M from EMD Millipore Category Protein Prices $2,709.00 Sizes 250 µg

Recombinant GRB2 Related Adaptor Protein 2 (GRAP2) - RPH967Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Search more