SLC22A17

Gene Symbol	SLC22A17
Entrez Gene	51310
Alt Symbol	24p3R, BOCT, BOIT, NGALR, NGALR2, NGALR3, hBOIT
Species	Human
Gene Type	protein-coding
Description	solute carrier family 22, member 17
Other Description	24p3 receptor|NGAL receptor|brain-type organic cation transporter|lipocalin-2 receptor|neutrophil gelatinase-associated lipocalin receptor|potent brain type organic ion transporter|solute carrier family 22 (organic cation transporter), member 17|solute carrier family 22 member 17
Swissprots	A8MUT0 Q9NQD5 Q9H1D3 A4UA13 Q5BKY8 Q2TAB0 Q86U04 Q8WUG5
Accessions	CAC17762 EAW66165 EAW66166 Q8WUG5 AJ243653 CAC01119 AK308661 AK311241 BC020565 AAH20565 BC030559 BC090870 AAH90870 BC111015 AAI11016 BF345519 BI758221 BX161416 CAD61891 BX647316 DQ658848 ABG45942 JF432878 ADZ16095 XM_005267747 XP_005267804 XM_005267748 XP_005267805 XR_245694 NM_001289050 NP_001275979 NM_016609 NP_057693 NM_020372 NP_065105 NR_110290
Function	Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17253959}; Multi-pass membrane protein {ECO:0000269|PubMed:17253959}. Vacuole membrane {ECO:0000269|PubMed:17253959}; Multi-pass membrane protein {ECO:0000269|PubMed:17253959}. Note=Upon LCN2-binding, it is internalized.
Tissue Specificity	Expressed in brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SLC22A17 full length protein - ab153343 from Abcam Category Protein Source Wheat germ Species Human

SLC22A17 Antibody Blocking Peptide - LS-E16157 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC22A17 Antibody Blocking Peptide - LS-E26821 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC22A17 Antibody Blocking Peptide - LS-E30519 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human SLC22A17 Protein - H00051310-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SLC22A17 Blocking Peptide - NBP1-76918PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human SLC22A17 Protein - H00051310-G01-10ug from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Species Human

SLC22A17 blocking peptide - GTX88612-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Slc22A17 Peptide - GTX85032-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

slc22A17 peptide - orb73207 from Biorbyt Category Peptide Prices $238.00 Sizes 500 µg

SLC22A17 Blocking Peptide - 33R-3704 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC22A17 Blocking Peptide - abx063857 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine

SLC22A17 Peptide - AC21-1653-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SLC22A17 - H00051310-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

SLC22A17 Control Peptide - AP30792CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Slc22A17 Peptide - 4651P from ProSci Category Peptide Species Human

SLC22A17 Peptide - 46-899P from ProSci Category Peptide

SLC22A17 fusion protein - ag3013 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

SLC22A17 Blocking Peptide - CBP2663 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine

SLC22A17 Peptide - abx164808 from Abbexa Category Peptide Species Human, Mouse, Rat

SLC22A17, Peptide - MBS425504 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

SLC22A17 Recombinant Protein Antigen - NBP1-88554PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SLC22A17 Peptide, Human - M34GP14381H from Creative Peptides Category Peptide Source Synthetic. Species Human

Solute carrier family 22 member 17 (SLC22A17), Recombinant Protein - MBS7094480 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

SLC22A17 peptide - orb218526 from Biorbyt Category Peptide Species Human, Mouse, Rat

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