SLC22A17

Gene Symbol SLC22A17
Entrez Gene 51310
Alt Symbol 24p3R, BOCT, BOIT, NGALR, NGALR2, NGALR3, hBOIT
Species Human
Gene Type protein-coding
Description solute carrier family 22, member 17
Other Description 24p3 receptor|NGAL receptor|brain-type organic cation transporter|lipocalin-2 receptor|neutrophil gelatinase-associated lipocalin receptor|potent brain type organic ion transporter|solute carrier family 22 (organic cation transporter), member 17|solute carrier family 22 member 17
Swissprots A8MUT0 Q9NQD5 Q9H1D3 A4UA13 Q5BKY8 Q2TAB0 Q86U04 Q8WUG5
Accessions CAC17762 EAW66165 EAW66166 Q8WUG5 AJ243653 CAC01119 AK308661 AK311241 BC020565 AAH20565 BC030559 BC090870 AAH90870 BC111015 AAI11016 BF345519 BI758221 BX161416 CAD61891 BX647316 DQ658848 ABG45942 JF432878 ADZ16095 XM_005267747 XP_005267804 XM_005267748 XP_005267805 XR_245694 NM_001289050 NP_001275979 NM_016609 NP_057693 NM_020372 NP_065105 NR_110290
Function Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17253959}; Multi-pass membrane protein {ECO:0000269|PubMed:17253959}. Vacuole membrane {ECO:0000269|PubMed:17253959}; Multi-pass membrane protein {ECO:0000269|PubMed:17253959}. Note=Upon LCN2-binding, it is internalized.
Tissue Specificity Expressed in brain.

BOCT (E-12) - sc-138147 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BOCT (P-12) - sc-138148 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SLC22A17 antibody - ab124506 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SLC22A17 antibody (ab124506) at 1 µg/mlLane 1 : SK-N-SH cell lysateLane 2 : SK-N-SH cell lysate with blocking peptideLysates/proteins at 15 µg per lane.

Anti-SLC22A17 Antibody (C-Terminus) - LS-C53320 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 50 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of Slc22A17 in Rat Kidney cells with Slc22A17 antibody at 20 ug/ml.

Anti-SLC22A17 Antibody (aa476-489) IHC-plus™ - LS-B3023 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-SLC22A17 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3023 concentration 2 ug/ml.

Anti-SLC22A17 Antibody (aa323-372) - LS-C110841 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SLC22A17 antibody LS-C110841 Western blot of DU145 cell lysate.

SLC22A17 Antibody - NBP1-76918 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SLC22A17 Antibody - NBP1-88554 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SLC22A17 Antibody [NBP1-88554] - Staining of human cell line U-251MG shows positivity in nucleus, nuclear membrane and cytoplasm.

SLC22A17 Antibody - NBP1-59889 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SLC22A17 Antibody [NBP1-59889] - DU145 cell lysate, concentration 0.2-1 ug/ml.

SLC22A17 Antibody - NBP1-20975 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Slc22A17 Polyclonal Antibody - bs-0444R from Bioss

Prices $279.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat colon carcinoma labeled with Anti-Slc22A17 Y Polyclonal Antibody, Unconjugated (bs-0444R) at 1:300, followed by conjugation to the secondary antibody and DAB staining

Slc22A17 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0444R-A350 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0444R-A488 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0444R-A555 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0444R-A647 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, Cy3 Conjugated - bs-0444R-Cy3 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, Cy5 Conjugated - bs-0444R-Cy5 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, Cy5.5 Conjugated - bs-0444R-Cy5.5 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, Cy7 Conjugated - bs-0444R-Cy7 from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, FITC Conjugated - bs-0444R-FITC from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, Biotin Conjugated - bs-0444R-Biotin from Bioss

Prices $359.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Slc22A17 Polyclonal Antibody, HRP Conjugated - bs-0444R-HRP from Bioss

Prices $379.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Slc22A17 antibody produced in rabbit - SAB3500306 from Sigma-Aldrich

Prices $348.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-Slc22A17: <B>Cat. No. SAB3500306</B>: Immunofluorescence of Slc22A17 in rat kidney tissue cells with Slc22A17 antibody at 20 μg/mL.

Anti-SLC22A17 antibody produced in rabbit - HPA002728 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC22A17: <B>Cat. No. HPA002728</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebral cortex tissue showing positive staining of neuronal cells.

SLC22A17 antibody - middle region (ARP43966_P050) - ARP43966_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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