H3F3B

Gene Symbol H3F3B
Entrez Gene 3021
Alt Symbol H3.3B
Species Human
Gene Type protein-coding
Description H3 histone, family 3B (H3.3B)
Other Description histone H3.3
Swissprots Q5VV56 Q5VV55 P84243 Q66I33
Accessions CAA88778 EAW89317 EAW89318 EAW89319 AF218029 AAG17271 AK054591 AK130772 AK304607 BAG65392 AK312762 BAG35628 AM393192 CAL38070 BC001124 AAH01124 BC006497 AAH06497 BC012813 AAH12813 BC017558 AAH17558 BC020466 BC108701 AAI08702 BM723811 BX537379 CAD97621 BX647280 DB466880 EU446957 ABZ92486 NM_005324 NP_005315
Function Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. {ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:15776021, ECO:0000269|PubMed:16258499}.
Subcellular Location Nucleus. Chromosome.
Top Pathways Systemic lupus erythematosus, Alcoholism, Transcriptional misregulation in cancer

Anti-Histone H3.3 Antibody (Lys27) - LS-C176600 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of Histone H3.3 (K27) pAb in paraffin-embedded human brain tissue.

Anti-Histone H3.3 Antibody (aa1-86) - LS-C186407 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded HSC3 xenograft using Histone H3.3B antibody at 1:500 dilution.

Anti-Histone H3.3 Antibody (aa100-150) - LS-C143900 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody - LS-C203510 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (Biotin) - LS-C203511 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (FITC) - LS-C203512 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (HRP) - LS-C203513 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody - LS-C203515 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3 Antibody (Ser10) - LS-C96594 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of Histone H3 in HL60 cell line lysates (35 ug/lane). Histone H3 (arrow) was detected using the purified antibody.

Anti-Histone H3.3 Antibody (phospho-Ser31) - LS-C199065 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HeLa cells, using Histone H3.3 (Phospho-Ser31) Antibody. The sample on the right was incubated with synthetic peptide.

Anti-Histone H3.3 Antibody - LS-C203589 from LifeSpan Bioscience

Prices $545.00
Sizes 25 tst
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (Biotin) - LS-C211128 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (aa28-77) - LS-C151417 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
H3F3A antibody Western Blot of Mouse Spleen.

Anti-Histone H3.3 Antibody - LS-C211131 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (aa16-65) - LS-C117808 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain, using Histone H3.3 (Ab-31) Antibody. The picture on the right is treated with the synthesized peptide.

Anti-Histone H3.3 Antibody (HRP) - LS-C211130 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (HRP) - LS-C318634 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (FITC) - LS-C211129 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (Biotin) - LS-C318637 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (FITC) - LS-C318635 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Histone H3.3 Antibody (aa100-150) IHC-plus™ - LS-B7958 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-H3F3A antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7958 dilution 10 ug/ml.

Anti-Histone H3.3 Antibody (phospho-Ser31, clone EPR1873) - LS-C105605 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR1873
IHC of paraffin-embedded human cervical carcinoma using anti-Histone H3.3 antibody (LS-C105605).

Anti-Histone H3.3 Antibody - LS-C319055 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Histone H3.3 antibody at 2 ug/ml with HeLa whole cell lysate secondary Goat polyclonal to rabbit at 1:10000 dilution predicted band size: 15 KDa observed band size: 15 KDa.

Anti-Histone H3.3 Antibody (clone 2D7-H1) IHC-plus™ - LS-B8442 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2D7-H1
Anti-H3F3B antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8442 dilution 15 ug/ml.

Histone H3.3 Antibody - NBP2-24697 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
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