H3F3B

Gene Symbol H3F3B
Entrez Gene 3021
Alt Symbol H3.3B
Species Human
Gene Type protein-coding
Description H3 histone, family 3B (H3.3B)
Other Description histone H3.3
Swissprots Q5VV56 Q5VV55 P84243 Q66I33
Accessions CAA88778 EAW89317 EAW89318 EAW89319 AF218029 AAG17271 AK054591 AK130772 AK304607 BAG65392 AK312762 BAG35628 AM393192 CAL38070 BC001124 AAH01124 BC006497 AAH06497 BC012813 AAH12813 BC017558 AAH17558 BC020466 BC108701 AAI08702 BM723811 BX537379 CAD97621 BX647280 DB466880 EU446957 ABZ92486 NM_005324 NP_005315
Function Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. {ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:15776021, ECO:0000269|PubMed:16258499}.
Subcellular Location Nucleus. Chromosome.
Top Pathways Systemic lupus erythematosus, Alcoholism, Transcriptional misregulation in cancer

Histone H3.3, ELISA Kit - MBS282201 from MyBioSource

Category ELISA Kit
Prices $465.00, $790.00, $3,500.00, $6,655.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Histone H3.3 ELISA Kit - EKE55638 from Biomatik

Category ELISA Kit
Prices $685.00, $2,913.00, $5,483.00
Sizes 96 t, 5x96t, 10x96t
Range 0.312-20 ng/mL

Human H3F3B ELISA Kit - E017834 from Biobool

Category ELISA Kit
Sensitivity 0.06 ng/ml.

anti-Histone H3.3 antibody [RM190] - ARG57230 from Arigo Biolaboratories

Category ELISA Kit

Histone H3.3 (H3f3b), ELISA Kit - MBS2610537 from MyBioSource

Category ELISA Kit
Prices $300.00, $475.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Histone H3.3 (H3f3b), ELISA Kit - MBS2603056 from MyBioSource

Category ELISA Kit
Prices $275.00, $420.00, $1,615.00, $2,880.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.06 ng/ml.
Range 20 ng/ml-0.312 ng/ml
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