H3F3B

Gene Symbol H3F3B
Entrez Gene 3021
Alt Symbol H3.3B
Species Human
Gene Type protein-coding
Description H3 histone, family 3B (H3.3B)
Other Description histone H3.3
Swissprots Q5VV56 Q5VV55 P84243 Q66I33
Accessions CAA88778 EAW89317 EAW89318 EAW89319 AF218029 AAG17271 AK054591 AK130772 AK304607 BAG65392 AK312762 BAG35628 AM393192 CAL38070 BC001124 AAH01124 BC006497 AAH06497 BC012813 AAH12813 BC017558 AAH17558 BC020466 BC108701 AAI08702 BM723811 BX537379 CAD97621 BX647280 DB466880 EU446957 ABZ92486 NM_005324 NP_005315
Function Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. {ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:15776021, ECO:0000269|PubMed:16258499}.
Subcellular Location Nucleus. Chromosome.
Top Pathways Systemic lupus erythematosus, Alcoholism, Transcriptional misregulation in cancer

Recombinant Human Histone H3.3B Protein - H00003021-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human Histone H3.3B Protein - H00003021-P02 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

H3F3A protein (His tag) - 80R-2788 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

H3F3B fusion protein - Ag0326 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Histone H3.3 (Human) - 31295 from ActiveMotif

Prices $95.00, $475.00
Sizes 100 µg, 1 mg
Source E. coli
Species Human
Recombinant Histone H3. 3 protein gel. Recombinant Histone H3. 3 run on an SDS-PAGE gel and stained with Coomassie blue.

H3, 1-18, K4Me2/K9Ac/K14Ac - 000-001-K48 from Rockland Immunochemicals Inc

Category Peptide
Prices $245.00
Sizes 1 mg

H3,21-44K36Me3,Biot - 000-006-K23 from Rockland Immunochemicals Inc

Category Peptide
Prices $285.00
Sizes 1 mg

H31-16K4Me3 - 000-001-K41 from Rockland Immunochemicals Inc

Category Peptide
Prices $195.00
Sizes 1 mg

H31-21K4Me2 - 000-001-K38 from Rockland Immunochemicals Inc

Category Peptide
Prices $225.00
Sizes 1 mg

H31-22,Biotin - 000-006-K27 from Rockland Immunochemicals Inc

Category Peptide
Prices $239.00
Sizes 1 mg

H321-44K27me1 - 000-001-K15 from Rockland Immunochemicals Inc

Category Peptide
Prices $255.00
Sizes 1 mg

H321-44K27me2 - 000-001-K16 from Rockland Immunochemicals Inc

Category Peptide
Prices $225.00
Sizes 1 mg

H321-44K27me3 - 000-001-K17 from Rockland Immunochemicals Inc

Category Peptide
Prices $239.00
Sizes 1 mg

H3K9Me1,1-21,Biot - 000-006-K31 from Rockland Immunochemicals Inc

Category Peptide
Prices $299.00
Sizes 1 mg

H3K9Me2,1-21,Biot - 000-006-K32 from Rockland Immunochemicals Inc

Category Peptide
Prices $265.00
Sizes 1 mg

H3K9Me3,1-21,Biot - 000-006-K33 from Rockland Immunochemicals Inc

Category Peptide
Prices $285.00
Sizes 1 mg

Histone H3 (101-115) Biotin Conjugated - 000-006-K70 from Rockland Immunochemicals Inc

Category Peptide
Prices $139.00
Sizes 1 mg

Histone H3 (106-120) Biotin Conjugated - 000-006-K71 from Rockland Immunochemicals Inc

Category Peptide
Prices $139.00
Sizes 1 mg

Histone H3 (111-125) Biotin Conjugated - 000-006-K72 from Rockland Immunochemicals Inc

Category Peptide
Prices $139.00
Sizes 1 mg

Histone H3 (11-25) Biotin Conjugated - 000-006-K52 from Rockland Immunochemicals Inc

Category Peptide
Prices $139.00
Sizes 1 mg

Histone H3 (116-130) Biotin Conjugated - 000-006-K73 from Rockland Immunochemicals Inc

Category Peptide
Prices $139.00
Sizes 1 mg

Histone H3 (121-135) Biotin Conjugated - 000-006-K74 from Rockland Immunochemicals Inc

Category Peptide
Prices $139.00
Sizes 1 mg

Histone H3 (16-30) Biotin Conjugated - 000-006-K53 from Rockland Immunochemicals Inc

Category Peptide
Prices $165.00
Sizes 1 mg

Histone H3 (36-50) Biotin Conjugated - 000-006-K57 from Rockland Immunochemicals Inc

Category Peptide
Prices $139.00
Sizes 1 mg

Histone H3 (41-55) Biotin Conjugated - 000-006-K58 from Rockland Immunochemicals Inc

Category Peptide
Prices $139.00
Sizes 1 mg
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