IPO4

Gene Symbol	IPO4
Entrez Gene	79711
Alt Symbol	Imp4
Species	Human
Gene Type	protein-coding
Description	importin 4
Other Description	imp4b\|importin-4\|importin-4b\|ran-binding protein 4\|ranBP4
Swissprots	B2RN95 Q8NCG8 Q2NL96 Q8TEX9 Q96SJ3 Q9H5L0 Q86TZ9 Q9BTI4
Accessions	EAW66078 EAW66079 EAW66080 EAW66081 EAW66082 EAW66083 EAW66084 EAW66085 EAW66086 EAW66087 EAW66088 Q8TEX9 AB208897 BAD92134 AF411122 AAL78660 AK026991 BAB15616 AK027871 BAB55421 AK056527 AK056702 BAG51791 AK057044 BAG51851 AK057277 BAG51895 AK074743 BAC11174 AK094107 BAG52816 AK094897 BAG52950 AK095306 BAG53025 AK302097 BAG63479 AK314305 BC003690 AAH03690 BC110804 AAI10805 BC136759 AAI36760 BC144399 BC144400 BF001674 BG333193 BX248267 CAD62595 CR457367 CAG33648 NM_024658 NP_078934 NR_051979
Function	Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. {ECO:0000250, ECO:0000269\|PubMed:11823430}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Ran BP-4 (N-15) - sc-55280 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Ran BP-4 (N-15): sc-55280. Western blot analysis of Ran BP-4 expression in Hep G2 (A), A549 (B) and HeLa (C) whole cell lysates.

Ran BP-4 (T-19) - sc-55283 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Ran BP-4 (T-19): sc-55283. Western blot analysis of Ran BP-4 expression in SK-N-MC (A) and A549 (B) nuclear extracts.

Ran BP-4 (H-300) - sc-292402 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Ran BP-4 (C-15) - sc-55276 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-Importin4 antibody - ab28387 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Importin4 antibody (ab28387) at 1 µg/mlLane 1 : Hela B Cell Lysate at 30 µgLane 2 : Hela B Cell Lysate at 60 µg

Anti-Importin4 antibody - ab198021 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Importin4 antibody (ab198021) at 1/550 dilutionLane 1 : HeLa cell lysateLane 2 : Human testis tissue lysateLane 3 : A549 cell lysateLane 4 : Jurkat cell lysateLane 5 : K562 cell lysateLysates/proteins at 40 µg per lane.

Anti-Importin4 antibody - ab99270 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling Importin4 with ab99270 at 1/5000 (0.2µg/mg). Detection: DAB.

Anti-Importin4 antibody - ab99271 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Importin4 antibody [EPR13660] - ab181046 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR13660

All lanes : Anti-Importin4 antibody [EPR13660] (ab181046) at 1/100000 dilutionLane 1 : HepG2 cell lysateLane 2 : HeLa cell lysateLane 3 : A549 cell lysateLane 4 : Human seminoma lysateLysates/proteins at 10 µg per lane.

Anti-Importin4 antibody [EPR13660-27] - ab181037 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR13660-27

All lanes : Anti-Importin4 antibody [EPR13660-27] (ab181037) at 1/10000 dilutionLane 1 : HepG2 lysatesLane 2 : HeLa lysatesLane 3 : A549 lysatesLane 4 : Human seminoma lysatesLane 5 : PC-12 lysatesLysates/proteins at 10 µg per lane.

Anti-IMP4 Antibody (C-Terminus) - LS-C151909 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

IMP4 / BXDC4 antibody Western Blot of HepG2.

Anti-IMP4 Antibody (aa215-243) - LS-C165226 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

IMP4 Antibody IHC of formalin-fixed and paraffin-embedded human testis carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-IMP4 Antibody (aa102-281) - LS-C178526 from LifeSpan Bioscience

Prices	$255.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IMP4 Antibody (aa215-243, APC) - LS-C236596 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IMP4 Antibody (aa215-243, AP) - LS-C236595 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IMP4 Antibody (aa215-243, Biotin) - LS-C236598 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IMP4 Antibody (aa215-243, FITC) - LS-C236599 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IMP4 Antibody (aa215-243, PE) - LS-C236601 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IMP4 Antibody (aa215-243, Azide-free, HRP) - LS-C249272 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IMP4 Antibody (aa222-251) - LS-C322234 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IPO4 Antibody (aa468-517) - LS-C169997 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IPO4 Antibody (aa900-950) - LS-C289446 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human Importin 4 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Importin 4 used at a dilution of 1:5000 (0.2 ug/mg).

Anti-IPO4 Antibody (aa350-400) - LS-C289443 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IPO4 Antibody (aa136-289) - LS-C178633 from LifeSpan Bioscience

Prices	$255.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Importin4 Antibody - NBP1-46166 from Novus Biologicals

Prices	$369.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: Importin4 Antibody [NBP1-46166] - Human ovarian carcinoma. Antibody used at a dilution of 1:5,000 (0.2ug/mg).

Search more