GSG2

Gene Symbol	GSG2
Entrez Gene	83903
Alt Symbol	HASPIN
Species	Human
Gene Type	protein-coding
Description	germ cell associated 2 (haspin)
Other Description	H-haspin\|germ cell-specific gene 2 protein\|haploid germ cell-specific nuclear protein kinase\|serine/threonine-protein kinase haspin
Swissprots	Q9BXS7 Q8TF76 Q96MN1 Q5U5K3
Accessions	EAW90481 Q8TF76 AB039834 BAB21938 AF289865 AAK30300 AK056691 BAB71255 AK292715 BAF85404 AK310546 AK315247 BC016626 AAH16626 BC036181 BC047457 AAH47457 BC050662 NM_031965 NP_114171
Function	Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle. {ECO:0000269\|PubMed:11228240, ECO:0000269\|PubMed:15681610, ECO:0000269\|PubMed:17084365, ECO:0000269\|PubMed:20705812, ECO:0000269\|PubMed:20929775}.
Subcellular Location	Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis.
Tissue Specificity	Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferating cell lines. {ECO:0000269\|PubMed:11228240, ECO:0000269\|PubMed:11311556}.

Haspin (H-300) - sc-98622 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Haspin (H-300): sc-98622. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing cytoplasmic staining of Perkinje cells and cells in granular and molecular layers.

Haspin (S-20) - sc-46004 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-Haspin antibody - ab21686 from Abcam

Prices	$370.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Haspin antibody (ab21686) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate at 10 µgLane 2 : HeLa Expressing myc-Haspin (interphase) Whole Cell Lysate - Positive Control at 5 µlLane 3 : HeLa Interphase Whole Cell Lysate - Negative Control at 10 µgLane 4 : HeLa Expressing myc-Haspin (mitosis) Whole Cell Lysate - Positive Control at 5 µlLane 5 : HeLa Mitosis Whole Cell Lysate - Negative Control at 10 µgSecondaryGoat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilutionPerformed under reducing conditions.

Anti-Haspin antibody - ab115800 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Haspin antibody (ab115800) at 1 µg/ml + Human placenta lysate at 10 µg

Anti-Haspin antibody - ab117791 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ab117791 at 1/250 dilution staining Haspin in Formalin-fixed, Paraffin-embedded Human prostate carcinoma tissue by Immunohistochemistry. Detection: DAB staining.

Anti-Haspin antibody - ab167204 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-Haspin antibody (ab167204) at 1 µg/mlLane 1 : Lysate of 293T cells transfected with Haspin.Lane 2 : Lysate of 293T cells (non-transfected)Lysates/proteins at 15 µl per lane.SecondaryGoat anti-mouse HRP conjugated antibody at 1/2500 dilution

Anti-GSG2 / HASPIN Antibody (Internal, AP) - LS-C277830 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-GSG2 / HASPIN Antibody (Internal, Biotin) - LS-C277832 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-GSG2 / HASPIN Antibody (Internal, APC) - LS-C277831 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-GSG2 / HASPIN Antibody (Internal, Azide-free, HRP) - LS-C277834 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-GSG2 / HASPIN Antibody (Internal, FITC) - LS-C277833 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-GSG2 / HASPIN Antibody (Internal, PE) - LS-C277835 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-GSG2 / HASPIN Antibody - LS-C309260 from LifeSpan Bioscience

Prices	$455.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-GSG2 / HASPIN Antibody (Internal) - LS-C330462 from LifeSpan Bioscience

Prices	$425.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-GSG2 / HASPIN Antibody (aa220-269) - LS-C145606 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

GSG2 antibody LS-C145606 Western blot of Placenta lysate. Antibody concentration 1 ug/ml.

Anti-GSG2 / HASPIN Antibody (aa306-355) - LS-C135819 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

GSG2 antibody LS-C135819 Western blot of 721_B cell lysate.

Anti-GSG2 / HASPIN Antibody (aa300-350) - LS-C286876 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human Haspin by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-Haspin used at a dilution of 1:250.

Anti-GSG2 / HASPIN Antibody (aa300-350) - LS-C288992 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

GSG2 Antibody - NBP1-81774 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: GSG2 Antibody [NBP1-81774] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-255

GSG2 Antibody - NBP1-26626 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: GSG2 Antibody [NBP1-26626] - Whole cell lysate from HeLa and 293T cells.

GSG2 Antibody - NBP1-79837 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: GSG2 Antibody [NBP1-79837] - Human placenta Lysate 1ug/ml Gel Concentration 12%

GSG2 Antibody - NBP1-79836 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: GSG2 Antibody [NBP1-79836] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

GSG2 Antibody - H00083903-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: GSG2 Antibody [H00083903-B01P] - Analysis of GSG2 expression in transfected 293T cell line by GSG2 polyclonal antibody. Lane 1: GSG2 transfected lysate(88.50 KDa). Lane 2: Non-transfected lysate.

Haspin Polyclonal Antibody - bs-15413R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-GSG2 antibody produced in mouse - SAB1401881 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Polyclonal Anti-GSG2, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401881</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~88.50 kDa using GSG2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

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