GSG2

Gene Symbol GSG2
Entrez Gene 83903
Alt Symbol HASPIN
Species Human
Gene Type protein-coding
Description germ cell associated 2 (haspin)
Other Description H-haspin|germ cell-specific gene 2 protein|haploid germ cell-specific nuclear protein kinase|serine/threonine-protein kinase haspin
Swissprots Q9BXS7 Q8TF76 Q96MN1 Q5U5K3
Accessions EAW90481 Q8TF76 AB039834 BAB21938 AF289865 AAK30300 AK056691 BAB71255 AK292715 BAF85404 AK310546 AK315247 BC016626 AAH16626 BC036181 BC047457 AAH47457 BC050662 NM_031965 NP_114171
Function Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle. {ECO:0000269|PubMed:11228240, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:17084365, ECO:0000269|PubMed:20705812, ECO:0000269|PubMed:20929775}.
Subcellular Location Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis.
Tissue Specificity Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferating cell lines. {ECO:0000269|PubMed:11228240, ECO:0000269|PubMed:11311556}.

Active human Haspin protein fragment - ab104026 from Abcam

Category Protein
Prices $239.00, $352.00
Sizes 5 µg, 10 µg
Source Baculovirus infected sf9 cells
Species Human
SDS-PAGE showing ab104026 at approximately 64kDa.

Human Haspin full length protein - ab132239 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE stained with Coomassie Blue showing ab132239.

Human Haspin peptide - ab23532 from Abcam

Category Peptide

Human Haspin protein fragment - ab153547 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153547 on a 12.5% SDS-PAGE stained with Coomassie Blue.

GSG2 / HASPIN Antibody Blocking Peptide - LS-E22161 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GSG2 / HASPIN Antibody Blocking Peptide - LS-E22162 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human GSG2 Protein - H00083903-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

GSG2 Partial Recombinant Protein - H00083903-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

GSG2 Blocking Peptide - 33R-7513 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

GSG2 Blocking Peptide - 33R-10406 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

GSG2 / Haspin - H00083903-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

GSG2 / Haspin - H00083903-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

GSG2 / Haspin - H00083903-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

GSG2 / Haspin - H00083903-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

GSG2 / Haspin - P5558 from Acris Antibodies

Category Protein
Prices $1,010.00
Sizes 5 µg
Species Human

Recombinant Human Germ Cell Associated 2 (haspin), GST-tagged - GSG2-1586H from Creative Biomart

Category Protein
Species Human

Recombinant Human GSG2 - GSG2-29180TH from Creative Biomart

Category Protein

Haspin Protein, active, 10 µg - 14-744 from EMD Millipore

Category Protein
Prices $401.00
Sizes 10 µg
Source Recombinant enzyme expressed in Sf21 cells

Haspin Protein, active, 250 µg - 14-744M from EMD Millipore

Category Protein
Prices $2,544.00
Sizes 250 µg also available in 10 μg size . (cat#14-744) and in bulk (cat# 14-744-K)
Source Recombinant enzyme expressed in Sf21 cells

Recombinant Human Serine/threonine-protein kinase haspin(GSG2) - CSB-YP819485HU CSB-EP819485HU CSB-BP819485HU CSB-MP819485HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

GSG2 Protein - NBP1-81774PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

GSG2-Antibody-Center-Blocking-peptide - BP8064c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

GSG2 Peptide, Human - M34GP06700H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

GSG2 Recombinant Protein Antigen - NBP2-55174PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Serine/threonine-protein kinase haspin (GSG2), Recombinant Protein - MBS1285881 from MyBioSource

Category Protein
Prices $1,620.00, $1,620.00, $1,845.00, $1,845.00, $2,785.00, $2,785.00, $3,245.00, $3,245.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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