GSG2

Gene Symbol GSG2
Entrez Gene 83903
Alt Symbol HASPIN
Species Human
Gene Type protein-coding
Description germ cell associated 2 (haspin)
Other Description H-haspin|germ cell-specific gene 2 protein|haploid germ cell-specific nuclear protein kinase|serine/threonine-protein kinase haspin
Swissprots Q9BXS7 Q8TF76 Q96MN1 Q5U5K3
Accessions EAW90481 Q8TF76 AB039834 BAB21938 AF289865 AAK30300 AK056691 BAB71255 AK292715 BAF85404 AK310546 AK315247 BC016626 AAH16626 BC036181 BC047457 AAH47457 BC050662 NM_031965 NP_114171
Function Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle. {ECO:0000269|PubMed:11228240, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:17084365, ECO:0000269|PubMed:20705812, ECO:0000269|PubMed:20929775}.
Subcellular Location Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis.
Tissue Specificity Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferating cell lines. {ECO:0000269|PubMed:11228240, ECO:0000269|PubMed:11311556}.

Haspin CRISPR/Cas9 KO Plasmid (h) - sc-403076 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin HDR Plasmid (h) - sc-403076-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin Double Nickase Plasmid (h) - sc-403076-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin Double Nickase Plasmid (h2) - sc-403076-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin CRISPR Activation Plasmid (h) - sc-403076-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin CRISPR Activation Plasmid (h2) - sc-403076-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin Lentiviral Activation Particles (h) - sc-403076-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin Lentiviral Activation Particles (h2) - sc-403076-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin siRNA (h) - sc-45797 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Haspin shRNA Plasmid (h) - sc-45797-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Haspin shRNA (h) Lentiviral Particles - sc-45797-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® siRNA - SIHK0868 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0867 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0866 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN9725 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9725 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GSG2 siRNA (Human) - CRJ3239 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GSG2 RNAi - H00083903-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GSG2 - MBS8213268 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Haspin CRISPR/Cas9 KO Plasmid (h2) - sc-403076-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haspin HDR Plasmid (h2) - sc-403076-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human GSG2 (NM_031965.2) - SHH308450 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GSG2(NM_031965.2) - SHH106697 from Creative biogene

Category siRNA
Species Reactivities Human

Human GSG2 siRNA - orb273740 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GSG2 shRNA Plasmid (Human) - CHJ3239 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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