CTIF

Gene Symbol	CTIF
Entrez Gene	9811
Alt Symbol	Gm672, KIAA0427
Species	Human
Gene Type	protein-coding
Description	CBP80/20-dependent translation initiation factor
Other Description	-
Swissprots	Q8IVD5 O43310 B3KTR8
Accessions	EAW62925 EAW62926 EAW62927 EAW62928 O43310 AB007887 BAA24857 AK095970 BAG53180 BC042146 AAH42146 BU688371 XM_005258392 XP_005258449 XM_006722583 XP_006722646 XM_006722585 XP_006722648 XM_006722586 XP_006722649 XM_006722587 XP_006722650 XM_006722588 XP_006722651 XM_006722589 XP_006722652 XM_011526278 XP_011524580 XM_011526279 XP_011524581 XM_011526280 XP_011524582 NM_001142397 NP_001135869 NM_014772 NP_055587
Function	Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the pioneer round of mRNA translation mediated by the cap-binding complex playing a central role in nonsense-mediated mRNA decay (NMD). {ECO:0000269|PubMed:19648179}.
Subcellular Location	Cytoplasm, perinuclear region {ECO:0000269|PubMed:19648179}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:19648179}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KIAA0427 full length protein - ab160663 from Abcam Category Protein Source Wheat germ Species Human

KIAA0427 / CTIF Antibody Blocking Peptide - LS-E14948 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CTIF Protein - H00009811-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

KIAA0427 Blocking Peptide - 33R-7783 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KIAA0427 Blocking Peptide - 33R-8789 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KIAA0427 - H00009811-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Recombinant Human CBP80/20-dependent translation initiation factor(CTIF) - CSB-YP012191HU CSB-EP012191HU CSB-BP012191HU CSB-MP012191HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CBP80/20-dependent translation initiation factor (CTIF), Recombinant Protein - MBS1189353 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,620.00, $1,620.00, $2,340.00, $2,340.00, $2,785.00, $2,785.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CTIF Recombinant Protein Antigen - NBP1-83008PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CTIF Recombinant Protein Antigen - NBP1-83007PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CTIF Peptide, Human - M34GP03796H from Creative Peptides Category Peptide Source Synthetic. Species Human

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