CTIF

Gene Symbol CTIF
Entrez Gene 9811
Alt Symbol Gm672, KIAA0427
Species Human
Gene Type protein-coding
Description CBP80/20-dependent translation initiation factor
Other Description -
Swissprots Q8IVD5 O43310 B3KTR8
Accessions EAW62925 EAW62926 EAW62927 EAW62928 O43310 AB007887 BAA24857 AK095970 BAG53180 BC042146 AAH42146 BU688371 XM_005258392 XP_005258449 XM_006722583 XP_006722646 XM_006722585 XP_006722648 XM_006722586 XP_006722649 XM_006722587 XP_006722650 XM_006722588 XP_006722651 XM_006722589 XP_006722652 XM_011526278 XP_011524580 XM_011526279 XP_011524581 XM_011526280 XP_011524582 NM_001142397 NP_001135869 NM_014772 NP_055587
Function Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the pioneer round of mRNA translation mediated by the cap-binding complex playing a central role in nonsense-mediated mRNA decay (NMD). {ECO:0000269|PubMed:19648179}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:19648179}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:19648179}.

Gm672 CRISPR/Cas9 KO Plasmid (h) - sc-411349 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gm672 HDR Plasmid (h) - sc-411349-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gm672 Double Nickase Plasmid (h) - sc-411349-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gm672 Double Nickase Plasmid (h2) - sc-411349-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gm672 CRISPR Activation Plasmid (h) - sc-411349-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gm672 CRISPR Activation Plasmid (h2) - sc-411349-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gm672 Lentiviral Activation Particles (h) - sc-411349-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gm672 Lentiviral Activation Particles (h2) - sc-411349-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gm672 siRNA (h) - sc-75155 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Gm672 shRNA Plasmid (h) - sc-75155-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Gm672 shRNA (h) Lentiviral Particles - sc-75155-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CTIF RNAi - H00009811-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU154441 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6732 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6732 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CTIF siRNA (Human) - CRH6567 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CTIF - MBS8207933 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CTIF (NM_014772.2) - SHH271233 from Creative biogene

Category siRNA
Species Reactivities Human

CTIF shRNA Plasmid (Human) - CHH6567 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CTIF miRNA 3'UTR clone - MiUTR4H-TG11562 from Creative biogene

Species Reactivities Human
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