CTIF

Gene Symbol CTIF
Entrez Gene 9811
Alt Symbol Gm672, KIAA0427
Species Human
Gene Type protein-coding
Description CBP80/20-dependent translation initiation factor
Other Description -
Swissprots Q8IVD5 O43310 B3KTR8
Accessions EAW62925 EAW62926 EAW62927 EAW62928 O43310 AB007887 BAA24857 AK095970 BAG53180 BC042146 AAH42146 BU688371 XM_005258392 XP_005258449 XM_006722583 XP_006722646 XM_006722585 XP_006722648 XM_006722586 XP_006722649 XM_006722587 XP_006722650 XM_006722588 XP_006722651 XM_006722589 XP_006722652 XM_011526278 XP_011524580 XM_011526279 XP_011524581 XM_011526280 XP_011524582 NM_001142397 NP_001135869 NM_014772 NP_055587
Function Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the pioneer round of mRNA translation mediated by the cap-binding complex playing a central role in nonsense-mediated mRNA decay (NMD). {ECO:0000269|PubMed:19648179}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:19648179}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:19648179}.

Gm672 (C-18) - sc-84828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Gm672 (E-19) - sc-84829 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-KIAA0427 antibody - ab82891 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KIAA0427 antibody (ab82891) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-KIAA0427 antibody - ab169390 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-KIAA0427 antibody (ab169390) at 1/500 dilutionLane 1 : KIAA0427 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-KIAA0427 / CTIF Antibody (aa36-85) - LS-C101872 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CTIF / KIAA0427 antibody LS-C101872 Western blot of HepG2 cell lysate.

Anti-KIAA0427 / CTIF Antibody (aa71-120) - LS-C110567 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CTIF / KIAA0427 antibody LS-C110567 Western blot of Fetal Small Intestine lysate.

CTIF Antibody - NBP1-83007 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CTIF Antibody [NBP1-83007] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

CTIF Antibody - NBP1-57319 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CTIF Antibody [NBP1-57319] - Human Small Intestine, concentration 0.2-1 ug/ml.

CTIF Antibody - NBP1-57423 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CTIF Antibody [NBP1-57423] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

CTIF Antibody - NBP1-83008 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CTIF Antibody [NBP1-83008] - Staining of human kidney shows strong cytoplasmic positivity in tubule cells.

CTIF Antibody - H00009811-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: CTIF Antibody [H00009811-B01] - analysis of KIAA0427 expression in transfected 293T cell line by KIAA0427 MaxPab polyclonal antibody (B01). Lane 1: KIAA0427 transfected lysate (67.60 KDa). Lane 2: Non-transfected lysate.

Anti-CTIF antibody produced in rabbit - HPA016865 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KIAA0427: <B>Cat. No. HPA016865</B>: Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

Anti-CTIF antibody produced in rabbit - HPA024801 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KIAA0427: <B>Cat. No. HPA024801</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in tubular cells.

Anti-KIAA0427 antibody produced in rabbit - SAB2101247 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KIAA0427: <B>Cat. No.SAB2101247</B>: KIAA0427 in HepG2 cell lysate with KIAA0427 antibody at 1.0 μg/mL.

Anti-KIAA0427, (N-terminal) antibody produced in rabbit - SAB2104595 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KIAA0427, antibody produced in rabbit: <B>Cat. No. SAB2104595</B>: Immunoblotting analysis of KIAA0427 in fetal Small intestine with KIAA0427 anitbody at 1 μg/mL.

KIAA0427 antibody - N-terminal region (ARP40788_P050) - ARP40788_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KIAA0427 antibody - N-terminal region (ARP40789_P050) - ARP40789_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KIAA0427 antibody, N-term - GTX47315 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

KIAA0427 antibody, N-term - GTX47316 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

KIAA0427 antibody - 70R-4775 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

KIAA0427 antibody - 70R-4855 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

KIAA0427 antibody - H00009811-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of KIAA0427 expression in transfected 293T cell line (H00009811-T01) by KIAA0427 MaxPab polyclonal antibody.Lane 1: KIA

KIAA0427 Antibody - 25-647 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

KIAA0427 Antibody - GWB-MN586A from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

KIAA0427 Antibody - GWB-MN587B from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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