VPS35

Gene Symbol VPS35
Entrez Gene 55737
Alt Symbol MEM3, PARK17
Species Human
Gene Type protein-coding
Description vacuolar protein sorting 35 homolog (S. cerevisiae)
Other Description hVPS35|maternal-embryonic 3|vacuolar protein sorting-associated protein 35
Swissprots Q561W2 Q96QK1 Q9H016 Q9NZK2 Q9H8J0 Q9NVG2 Q9NX80 Q9H4P3 Q9NRS7 Q9H096
Accessions EAW82683 EAW82684 Q96QK1 AF086051 AF175265 AAF89953 AF183418 AAG09687 AF186382 AAG40619 AF191298 AAF02778 AK000395 BAA91137 AK001614 BAA91790 AK023650 BAB14626 AK025774 AK223218 BAD96938 AL136888 CAB66822 AL512769 CAC21686 AM393740 CAL38615 AY007112 AAG01989 BC002414 AAH02414 BC010362 AAH10362 BC041367 BC093036 AAH93036 BM971213 BQ574179 BX647213 CAI46268 DB049686 XM_005256045 XP_005256102 XM_011523227 XP_011521529 NM_018206 NP_060676
Function Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of low affinity and retromer SNX proteins may also contribute to cargo selectivity thus questioning the classical function of the CSC. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved
Subcellular Location Cytoplasm. Membrane; Peripheral membrane protein. Endosome {ECO:0000269|PubMed:15078903}. Early endosome {ECO:0000305}. Late endosome {ECO:0000305}. Note=Localizes to tubular profiles adjacent to endosomes. {ECO:0000269|PubMed:15078903}.
Tissue Specificity Ubiquitous. Highly expressed in heart, brain, placenta, skeletal muscle, spleen, thymus, testis, ovary, small intestine, kidney and colon.

vacuolar protein sorting 35 homolog (S. cerevisiae) , ELISA Kit - MBS9323040 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 5.0 pg/ml.
Range 31.2 pg/ml - 1000 pg/ml.

Human VPS35 ELISA Kit - E102682 from Biobool

Category ELISA Kit

anti-VPS35 / MEM3 antibody - ARG63418 from Arigo Biolaboratories

Category ELISA Kit

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9347132 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388884 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9350228 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388892 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9360134 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388877 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9369354 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388880 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388878 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9351258 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388879 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9352015 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9346378 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388883 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388888 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9345202 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388881 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9353662 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388885 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9364362 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9388887 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vacuolar Protein Sorting-Associated Protein 35 (VPS35), ELISA Kit - MBS9354201 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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