Gene Symbol | ERBB3 |
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Entrez Gene | 2065 |
Alt Symbol | ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 |
Species | Human |
Gene Type | protein-coding |
Description | erb-b2 receptor tyrosine kinase 3 |
Other Description | human epidermal growth factor receptor 3|proto-oncogene-like protein c-ErbB-3|receptor tyrosine-protein kinase erbB-3|tyrosine kinase-type cell surface receptor HER3|v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 |
Swissprots | B4DIK7 B4DV32 A8K6L6 Q9BUD7 P21860 E9PDT8 |
Accessions | AAF86627 AAF86628 CCD32996 EAW96879 EAW96880 EAW96881 EAW96882 EAW96883 P21860 AA524528 AK124710 BAG54075 AK125028 BAG54127 AK291681 BAF84370 AK294719 BAG57868 AK295650 BAG58519 AK300909 BAG62544 AU100462 BC002706 AAH02706 BC041579 BC082992 AAH82992 BM837872 BT007226 AAP35890 BU674508 BX641868 DC344156 DC347955 M29366 AAA35790 M34309 AAA35979 S61953 AAB26935 U88357 AAC39857 U88358 AAC39858 U88359 AAC39859 U88360 AAC39860 NM_001005915 NP_001005915 NM_001982 NP_001973 |
Function | Binds and is activated by neuregulins and NTAK. May also be activated by CSPG5. {ECO:0000269|PubMed:15358134}. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Epithelial tissues and brain. |
Top Pathways | ErbB signaling pathway, Calcium signaling pathway, Endocytosis, MicroRNAs in cancer, Proteoglycans in cancer |
PathScan ® Phospho-HER3/ErbB3 (panTyr) Sandwich ELISA Kit - 7890 from Cell Signaling Technology
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PathScan ® Total HER3/ErbB3 Sandwich ELISA kit - 7888 from Cell Signaling Technology
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ErbB3 Human ELISA kit - ab100511 from Abcam
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Human Phospho-ERBB3 / HER3 (Tyr1222) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1364 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-ERBB3 / HER3 (Tyr1197) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1749 from LifeSpan Bioscience
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Mouse/Human/Rat ERBB3 / HER3 ELISA Kit (Cell-Based ELISA) - LS-F2047 from LifeSpan Bioscience
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Human ERBB3 / HER3 ELISA Kit (Sandwich ELISA) - LS-F78 from LifeSpan Bioscience
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Mouse ERBB3 / HER3 ELISA Kit (Sandwich ELISA) - LS-F8703 from LifeSpan Bioscience
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Human ERBB3 / HER3 ELISA Kit (Sandwich ELISA) - LS-F9464 from LifeSpan Bioscience
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Phosphotyrosine ERBB3 / Receptor Tyrosine-protein Kinase erbB-3 ELISA Kit - RAB0956 from Sigma-Aldrich
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Human ErbB3 / HER3 ELISA Kit - RAB0174 from Sigma-Aldrich
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Human Phospho-ErbB3/Her3 DuoSet IC Economy Pk, 15 Plate - DYC1769E from R&D Systems
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Human Phospho-ErbB3/Her3 DuoSet IC ELISA - DYC1769-2 from R&D Systems
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Human Phospho-ErbB3/Her3 DuoSet IC, 5 Plate - DYC1769-5 from R&D Systems
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Human Total ErbB3/Her3 DuoSet IC ELISA - DYC234-2 from R&D Systems
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Human Total ErbB3/Her3 DuoSet IC, 5 Plate - DYC234-5 from R&D Systems
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Human Phospho-ErbB3/Her3 (Y1262) Cell-Based ELISA - KCB5677 from R&D Systems
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Human ErbB3/Her3 DuoSet ELISA - DY348 from R&D Systems
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Human ErbB3 ELISA Kit - abx151441 from Abbexa
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Receptor tyrosine-protein kinase erbB-3 (ERBB3), Human, ELISA Kit - CSB-EL007765HU from ARP American Research Products
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Receptor tyrosine-protein kinase erbB-3, ERBB3, Human, ELISA Kit - E9313h from ARP American Research Products
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V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3), Human, ELISA Kit - SEC187Hu from ARP American Research Products
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Human ErbB3 ELISA - ELH-ErbB3 from RayBiotech
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Human Phospho-ErbB3 (Y1262) ELISA - PEL-ErbB3-Y1262 from RayBiotech
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V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3, ELISA Kit - MBS075529 from MyBioSource
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