ERBB3

Gene Symbol	ERBB3
Entrez Gene	2065
Alt Symbol	ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
Species	Human
Gene Type	protein-coding
Description	erb-b2 receptor tyrosine kinase 3
Other Description	human epidermal growth factor receptor 3|proto-oncogene-like protein c-ErbB-3|receptor tyrosine-protein kinase erbB-3|tyrosine kinase-type cell surface receptor HER3|v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Swissprots	B4DIK7 B4DV32 A8K6L6 Q9BUD7 P21860 E9PDT8
Accessions	AAF86627 AAF86628 CCD32996 EAW96879 EAW96880 EAW96881 EAW96882 EAW96883 P21860 AA524528 AK124710 BAG54075 AK125028 BAG54127 AK291681 BAF84370 AK294719 BAG57868 AK295650 BAG58519 AK300909 BAG62544 AU100462 BC002706 AAH02706 BC041579 BC082992 AAH82992 BM837872 BT007226 AAP35890 BU674508 BX641868 DC344156 DC347955 M29366 AAA35790 M34309 AAA35979 S61953 AAB26935 U88357 AAC39857 U88358 AAC39858 U88359 AAC39859 U88360 AAC39860 NM_001005915 NP_001005915 NM_001982 NP_001973
Function	Binds and is activated by neuregulins and NTAK. May also be activated by CSPG5. {ECO:0000269|PubMed:15358134}.
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Epithelial tissues and brain.
Top Pathways	ErbB signaling pathway, Calcium signaling pathway, Endocytosis, MicroRNAs in cancer, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® HER3/ErbB3 siRNA I - 6504 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

SignalSilence ® HER3/ErbB3 siRNA II - 6422 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

ErbB-3 CRISPR/Cas9 KO Plasmid (h) - sc-400146 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ErbB-3 HDR Plasmid (h) - sc-400146-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ErbB-3 Double Nickase Plasmid (h) - sc-400146-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ErbB-3 Double Nickase Plasmid (h2) - sc-400146-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ErbB-3 CRISPR Activation Plasmid (h) - sc-400146-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ErbB-3 CRISPR Activation Plasmid (h2) - sc-400146-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ErbB-3 Lentiviral Activation Particles (h) - sc-400146-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ErbB-3 Lentiviral Activation Particles (h2) - sc-400146-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ErbB-3 siRNA (h) - sc-35327 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ErbB-3 shRNA Plasmid (h) - sc-35327-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ErbB-3 shRNA (h) Lentiviral Particles - sc-35327-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ErbB-3 siRNA (h2) - sc-44298 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ErbB-3 shRNA Plasmid (h2) - sc-44298-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ErbB-3 shRNA (h2) Lentiviral Particles - sc-44298-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ErbB3/Her3 RNAi - H00002065-R07 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU030961 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® siRNA - SIHK0727 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0726 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0728 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN1248 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1248 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08672 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr08672

ERBB3 siRNA (Human) - CRH1440 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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