| Gene Symbol |
LHPP
|
| Entrez Gene |
64077
|
| Alt Symbol |
HDHD2B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
|
| Other Description |
hLHPP
|
| Swissprots |
Q9H008 Q5VUV9 Q2TBE9 Q5VUW0 B3KP20
|
| Accessions |
EAW49264 EAW49265 EAW49266 EAW49267 EAW49268 EAW49269 Q9H008 AK055532 BAG51532 BC007324 BC073172 BC110344 AAI10345 BC113629 AAI13630 BC113631 AAI13632 EF151005 HQ258160 ADR82914 XM_005270025 XP_005270082 XM_005270026 XP_005270083 XM_005270027 XP_005270084 XM_006717943 XP_006718006 XM_011540055 XP_011538357 XM_011540056 XP_011538358 XM_011540057 XP_011538359 XM_011540058 XP_011538360 XR_945797 NM_001167880 NP_001161352 NM_022126 NP_071409
|
| Function |
Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16430861}. Nucleus {ECO:0000269|PubMed:16430861}.
|
| Tissue Specificity |
Expressed in brain, and at lower levels in liver and kidney. Detected in thyroid (at protein level). Expressed in liver, kidney and moderately in brain. {ECO:0000269|PubMed:12801912, ECO:0000269|PubMed:16430861}.
|
| Top Pathways |
Oxidative phosphorylation
|
![Western Blot: LHPP Overexpression Lysate (Adult Normal) [NBP2-06465] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LHPP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10258_LHPP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06465-img0001.jpg)