Gene Symbol | LHPP |
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Entrez Gene | 64077 |
Alt Symbol | HDHD2B |
Species | Human |
Gene Type | protein-coding |
Description | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
Other Description | hLHPP |
Swissprots | Q9H008 Q5VUV9 Q2TBE9 Q5VUW0 B3KP20 |
Accessions | EAW49264 EAW49265 EAW49266 EAW49267 EAW49268 EAW49269 Q9H008 AK055532 BAG51532 BC007324 BC073172 BC110344 AAI10345 BC113629 AAI13630 BC113631 AAI13632 EF151005 HQ258160 ADR82914 XM_005270025 XP_005270082 XM_005270026 XP_005270083 XM_005270027 XP_005270084 XM_006717943 XP_006718006 XM_011540055 XP_011538357 XM_011540056 XP_011538358 XM_011540057 XP_011538359 XM_011540058 XP_011538360 XR_945797 NM_001167880 NP_001161352 NM_022126 NP_071409 |
Function | Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16430861}. Nucleus {ECO:0000269|PubMed:16430861}. |
Tissue Specificity | Expressed in brain, and at lower levels in liver and kidney. Detected in thyroid (at protein level). Expressed in liver, kidney and moderately in brain. {ECO:0000269|PubMed:12801912, ECO:0000269|PubMed:16430861}. |
Top Pathways | Oxidative phosphorylation |
LHPP (B-2) - sc-376648 from Santa Cruz Biotechnology
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LHPP (H-2) - sc-376527 from Santa Cruz Biotechnology
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LHPP (G-15) - sc-163016 from Santa Cruz Biotechnology
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LHPP (H-86) - sc-134671 from Santa Cruz Biotechnology
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LHPP (D-12) - sc-163015 from Santa Cruz Biotechnology
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Anti-LHPP antibody - ab102546 from Abcam
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Anti-LHPP Antibody (aa179-228) - LS-C116706 from LifeSpan Bioscience
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Anti-LHPP Antibody (C-Terminus) - LS-C169696 from LifeSpan Bioscience
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LHPP Antibody - NBP1-83272 from Novus Biologicals
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LHPP Antibody - NBP1-83273 from Novus Biologicals
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LHPP Antibody - NBP1-70600 from Novus Biologicals
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HDHD2B Polyclonal Antibody - bs-8319R from Bioss
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Anti-LHPP antibody produced in rabbit - HPA009163 from Sigma-Aldrich
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Anti-LHPP antibody produced in rabbit - HPA009269 from Sigma-Aldrich
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LHPP antibody - middle region (ARP57605_P050) - ARP57605_P050 from Aviva Systems Biology
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LHPP antibody - 70R-4027 from Fitzgerald
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LHPP antibody - 15759-1-AP from Acris Antibodies
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LHPP antibody - H00064077-B01P from Acris Antibodies
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LHPP antibody - 15759-1-AP from Proteintech Group
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LHPP, Polyclonal Antibody - MBS2522096 from MyBioSource
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LHPP Antibody - GWB-MU891I from Genway Biotech
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LHPP Antibody - EPP14929 from Elabscience
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HDHD2B Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-8319R-A350 from Bioss
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HDHD2B Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-8319R-A488 from Bioss
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HDHD2B Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-8319R-A555 from Bioss
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