Gene Symbol | LHPP |
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Entrez Gene | 64077 |
Alt Symbol | HDHD2B |
Species | Human |
Gene Type | protein-coding |
Description | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
Other Description | hLHPP |
Swissprots | Q9H008 Q5VUV9 Q2TBE9 Q5VUW0 B3KP20 |
Accessions | EAW49264 EAW49265 EAW49266 EAW49267 EAW49268 EAW49269 Q9H008 AK055532 BAG51532 BC007324 BC073172 BC110344 AAI10345 BC113629 AAI13630 BC113631 AAI13632 EF151005 HQ258160 ADR82914 XM_005270025 XP_005270082 XM_005270026 XP_005270083 XM_005270027 XP_005270084 XM_006717943 XP_006718006 XM_011540055 XP_011538357 XM_011540056 XP_011538358 XM_011540057 XP_011538359 XM_011540058 XP_011538360 XR_945797 NM_001167880 NP_001161352 NM_022126 NP_071409 |
Function | Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16430861}. Nucleus {ECO:0000269|PubMed:16430861}. |
Tissue Specificity | Expressed in brain, and at lower levels in liver and kidney. Detected in thyroid (at protein level). Expressed in liver, kidney and moderately in brain. {ECO:0000269|PubMed:12801912, ECO:0000269|PubMed:16430861}. |
Top Pathways | Oxidative phosphorylation |
Human LHPP full length protein - ab116175 from Abcam
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LHPP Antibody Blocking Peptide - LS-E21032 from LifeSpan Bioscience
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LHPP Recombinant Protein - P4537 from Novus Biologicals
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Recombinant Human LHPP Protein - NBP1-78818 from Novus Biologicals
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Human LHPP protein - orb168734 from Biorbyt
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LHPP Blocking Peptide - 33R-1067 from Fitzgerald
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LHPP protein (His tag) - 80R-2061 from Fitzgerald
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LHPP (1-270, His-tag) - AR50144PU-N from Acris Antibodies
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LHPP (1-270, His-tag) - AR50144PU-S from Acris Antibodies
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LHPP - P4537 from Acris Antibodies
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Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase, Human Recombinant - 228-12586-1 from RayBiotech
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Recombinant Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase - 228-12586-2 from RayBiotech
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Recombinant Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase - 228-12586-3 from RayBiotech
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LHPP, 1-270aa, Human, His tag, E.coli - 01-P1319 from ARP American Research Products
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LHPP fusion protein - Ag8375 from Proteintech Group
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LHPP fusion protein - ag8388 from Proteintech Group
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LHPP Human - ENPS-582 from NeoScientific
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Recombinant Human LHPP Enzyme - BP002715-ENZ-575 from Syd Labs
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LHPP, 1-270aa, Recombinant Protein - GWB-P0719D from Genway Biotech
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Recombinant Human Phospholysine PhosphoHistidine Inorganic Pyrophosphate Phosphatase, His-tagged - LHPP-1319H from Creative Biomart
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Recombinant Human LHPP, His-tagged - LHPP-28094TH from Creative Biomart
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LHPP 1-270aa - CMB-1152 from Reagent Proteins
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Recombinant Human Phospholysine phosphohistidine inorganic pyrophosphate phosphatase(LHPP) - CSB-YP867114HU CSB-EP867114HU CSB-BP867114HU CSB-MP867114HU from Cusabio
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LHPP, 1-270aa, Human, His tag, E.coli - ATGP1319 from ATGen
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Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase (Recombinant) - abx073789 from Abbexa |