HAND2

Gene Symbol	HAND2
Entrez Gene	9464
Alt Symbol	DHAND2, Hed, Thing2, bHLHa26, dHand
Species	Human
Gene Type	protein-coding
Description	heart and neural crest derivatives expressed 2
Other Description	basic helix-loop-helix transcription factor HAND2|class A basic helix-loop-helix protein 26|deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2|heart- and neural crest derivatives-expressed protein 2
Swissprots	P97833 Q494T1 B6ECG9 O95301 O95300 P61296
Accessions	AAD13186 EAX04749 EAX04750 P61296 AF087940 AAD13185 AK122739 BAG53697 BC101406 AAI01407 BC101974 AAI01975 BC109383 AAI09384 BF313018 FJ226608 ACI42790 NM_021973 NP_068808
Function	Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
Tissue Specificity	Heart.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HAND2 full length protein - ab152991 from Abcam Category Protein Source Wheat germ Species Human

Human HAND2 protein fragment - ab152992 from Abcam Category Protein Source Wheat germ Species Human

DHAND / HAND2 Antibody Blocking Peptide - LS-E4646 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DHAND / HAND2 Antibody Blocking Peptide - LS-E8081 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DHAND / HAND2 Antibody Blocking Peptide - LS-E26414 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HAND2 Protein - H00009464-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human HAND2 Protein - H00009464-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HAND2 Peptide - P1727 from Novus Biologicals Category Peptide Species Human

HAND2-Antibody-Center-Blocking-Peptide - BP17008c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HAND2-Antibody-C-term-Blocking-Peptide - BP6117a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Hand2 Blocking Peptide - 33R-2133 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HAND2 Peptide - AC21-1253-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

HAND2 / DHAND - H00009464-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

HAND2 / DHAND - H00009464-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HAND2 / DHAND - H00009464-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HAND2 fusion protein - Ag16038 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human HAND2, GST-tagged - HAND2-13663H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Gap Junction Protein Beta 6 (GJb6) - RPE196Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Heart- and neural crest derivatives-expressed protein 2(HAND2) - CSB-YP010126HU CSB-EP010126HU CSB-BP010126HU CSB-MP010126HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HAND2 Peptide, Human - M34GP06829H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human HAND2 protein - orb54396 from Biorbyt Category Protein Prices $289.00, $408.00, $476.00, $765.00, $1,275.00, $2,023.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

HAND2 Recombinant Protein Antigen - NBP2-58062PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Heart-and neural crest derivatives-expressed protein 2 (HAND2), Recombinant Protein - MBS962102 from MyBioSource Category Protein Prices $970.00, $970.00, $1,190.00, $1,190.00, $1,455.00, $1,455.00, $1,920.00, $1,920.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

HAND2 Recombinant Protein (Human) (OPCA04883) - OPCA04883 from Aviva Systems Biology Category Protein Species Human

Recombinant Human HAND2 Protein, GST-tagged - HAND2-4568H from Creative Biomart Category Protein Source Wheat Germ Species Human

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