Gene Symbol | CCDC53 |
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Entrez Gene | 51019 |
Alt Symbol | CGI-116 |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil domain containing 53 |
Other Description | WASH complex subunit CCDC53|coiled-coil domain-containing protein 53 |
Swissprots | B2RC74 Q9Y3C0 Q53FF0 Q96QK0 Q6IAI4 |
Accessions | EAW97687 Q9Y3C0 AF151874 AAD34111 AF155655 AAF67012 AI739611 AK223339 BAD97059 AK314970 BAG37471 BC010889 AAH10889 BX356987 CR457171 CAG33452 DB452335 HQ448683 ADQ33161 XM_011538423 XP_011536725 NM_001301107 NP_001288036 NM_016053 NP_057137 |
Function | Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). {ECO:0000269|PubMed:19922875, ECO:0000269|PubMed:20498093}. |
Subcellular Location | Early endosome {ECO:0000305}. |
CCDC53 (N-17) - sc-242371 from Santa Cruz Biotechnology
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Anti-CCDC53 antibody - ab122461 from Abcam
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coiled-coil domain containing 53 Antibody - NBP2-38406 from Novus Biologicals
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coiled-coil domain containing 53 Antibody - NBP1-84521 from Novus Biologicals
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Anti-CCDC53 (166-180) antibody produced in rabbit - SAB1101801 from Sigma-Aldrich
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Anti-CCDC53 antibody produced in rabbit - HPA038338 from Sigma-Aldrich
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CCDC53 antibody - 24445-1-AP from Acris Antibodies
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CCDC53 antibody - 24445-1-AP from Proteintech Group
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Anti-CCDC53 (aa 8-88) polyclonal antibody - DPABH-20763 from Creative Diagnostics
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Anti-CCDC53 monoclonal antibody - DCABH-200338 from Creative Diagnostics
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Anti-CCDC53 Antibody - ABT69 from EMD Millipore
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CCDC53 antibody - AP56117PU-N from Acris Antibodies
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Anti-CCDC53 antibody produced in rabbit - HPA038339 from Sigma-Aldrich
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Anti-CCDC53 Antibody - ABT69 from Sigma-Aldrich
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CCDC53 Antibody,HRP conjugated - CSB-PA896504LB01HU from Cusabio
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CCDC53 Antibody,FITC conjugated - CSB-PA896504LC01HU from Cusabio
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CCDC53 Antibody,Biotin conjugated - CSB-PA896504LD01HU from Cusabio
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CCDC53 Antibody - CSB-PA896504LA01HU from Cusabio
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anti-CCDC53 antibody - A001361 from Biobool
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CCDC53, Polyclonal Antibody - MBS1499239 from MyBioSource
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CCDC53, Polyclonal Antibody - MBS1493112 from MyBioSource
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CCDC53, Polyclonal Antibody - MBS1492160 from MyBioSource
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CCDC53, Polyclonal Antibody - MBS1499379 from MyBioSource
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Anti-CCDC53 Antibody (HRP) - LS-C380296 from LifeSpan Bioscience
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Anti-CCDC53 Antibody - LS-C380297 from LifeSpan Bioscience
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