CCDC53

Gene Symbol CCDC53
Entrez Gene 51019
Alt Symbol CGI-116
Species Human
Gene Type protein-coding
Description coiled-coil domain containing 53
Other Description WASH complex subunit CCDC53|coiled-coil domain-containing protein 53
Swissprots B2RC74 Q9Y3C0 Q53FF0 Q96QK0 Q6IAI4
Accessions EAW97687 Q9Y3C0 AF151874 AAD34111 AF155655 AAF67012 AI739611 AK223339 BAD97059 AK314970 BAG37471 BC010889 AAH10889 BX356987 CR457171 CAG33452 DB452335 HQ448683 ADQ33161 XM_011538423 XP_011536725 NM_001301107 NP_001288036 NM_016053 NP_057137
Function Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). {ECO:0000269|PubMed:19922875, ECO:0000269|PubMed:20498093}.
Subcellular Location Early endosome {ECO:0000305}.

CCDC53 CRISPR/Cas9 KO Plasmid (h) - sc-408224 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC53 HDR Plasmid (h) - sc-408224-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC53 Double Nickase Plasmid (h) - sc-408224-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC53 Double Nickase Plasmid (h2) - sc-408224-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC53 CRISPR Activation Plasmid (h) - sc-408224-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC53 CRISPR Activation Plasmid (h2) - sc-408224-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC53 Lentiviral Activation Particles (h) - sc-408224-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC53 Lentiviral Activation Particles (h2) - sc-408224-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC53 siRNA (h) - sc-95751 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCDC53 shRNA Plasmid (h) - sc-95751-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCDC53 shRNA (h) Lentiviral Particles - sc-95751-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU147211 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5536 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5536 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00391 from Sigma-Aldrich

Category miRNA

CCDC53 siRNA (Human) - CRH9459 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCDC53 - MBS8234609 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CCDC53 (NM_016053.2) - SHH256781 from Creative biogene

Category siRNA
Species Reactivities Human

CCDC53 shRNA Plasmid (Human) - CHH9459 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CCDC53 miRNA 3'UTR clone - MiUTR1H-01755 from Creative biogene

Species Reactivities Human
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