CCDC53

Gene Symbol	CCDC53
Entrez Gene	51019
Alt Symbol	CGI-116
Species	Human
Gene Type	protein-coding
Description	coiled-coil domain containing 53
Other Description	WASH complex subunit CCDC53|coiled-coil domain-containing protein 53
Swissprots	B2RC74 Q9Y3C0 Q53FF0 Q96QK0 Q6IAI4
Accessions	EAW97687 Q9Y3C0 AF151874 AAD34111 AF155655 AAF67012 AI739611 AK223339 BAD97059 AK314970 BAG37471 BC010889 AAH10889 BX356987 CR457171 CAG33452 DB452335 HQ448683 ADQ33161 XM_011538423 XP_011536725 NM_001301107 NP_001288036 NM_016053 NP_057137
Function	Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). {ECO:0000269|PubMed:19922875, ECO:0000269|PubMed:20498093}.
Subcellular Location	Early endosome {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CCDC53-Over-expression-Lysate - LY13619a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

CCDC53 overexpression lysate - LY414219 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CCDC53 293 Cell Lysate - 406836 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

coiled-coil domain containing 53 Overexpression Lysate (Native) - NBL1-08804 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CCDC53 Over-expression Lysate Product - GWB-F2355C from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human CCDC53 Knockdown Stable Cell Line - CSC-DC002552 from Creative biogene Category Cell Line Species Human

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