Pik3r1

Gene Symbol	Pik3r1
Entrez Gene	18708
Alt Symbol	PI3K, p50alpha, p55alpha, p85alpha
Species	Mouse
Gene Type	protein-coding
Description	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
Other Description	PI3-kinase subunit p85-alpha|PI3K regulatory subunit alpha|phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha|phosphatidylinositol 3-kinase regulatory subunit alpha
Swissprots	Q8K3B3 P26450
Accessions	EDL00772 P26450 AI838690 AK046259 AK049798 BAC33923 AK138868 BAE23803 AK160493 AK164783 BAE37914 AK171366 BB647657 BC002168 AAH02168 BC026146 AAH26146 BC051106 AAH51106 BM963795 BY276314 CB519962 CF169061 M60651 AAA39886 U50413 AAC52847 U50414 AAC52848 XM_006517569 XP_006517632 XM_006517570 XP_006517633 NM_001024955 NP_001020126 NM_001077495 NP_001070963
Function	Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (By similarity). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348926). {ECO:0000250, ECO:0000269|PubMed:20348926}.
Top Pathways	Apoptosis, VEGF signaling pathway, Focal adhesion, Toll-like receptor signaling pathway, Jak-STAT signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Anti-PIK3R1 antibody produced in rabbit - SAB2106248 from Sigma-Aldrich Prices $341.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Pik3r1 antibody - C-terminal region (ARP32121_P050) - ARP32121_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Mouse-Pik3r1-Antibody-N-term - AP19794a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

Mouse Pik3r1 Antibody - N-terminal region (OAAB15277) - OAAB15277 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

PIK3R1 antibody (Tyr607) - 70R-34985 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Mouse Pik3r1 Antibody - abx031214 from Abbexa Host Rabbit Clonality Polyclonal

Rabbit Anti-Mouse Mouse Pik3r1 (N-term) - 102-14420 from RayBiotech Host Rabbit

Pik3r1 antibody (N-term) - STJ47737 from St John's Laboratory Ltd Host Rabbit Clonality Polyclonal Clone RB40862

Pik3r1 Antibody - GWB-ML252I from Genway Biotech Prices $368.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

PIK3R1 antibody - 70R-51605 from Fitzgerald Prices $395.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

PI3K p85 alpha antibody - 70R-50209 from Fitzgerald Prices $395.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Pik3r1, Polyclonal Antibody - MBS9213829 from MyBioSource Prices $155.00, $340.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

anti-PI3 Kinase p85/p55 antibody - ARG51366 from Arigo Biolaboratories

anti-PI3K P85 / p55 phospho (Tyr467 / Tyr199) antibody - ARG51810 from Arigo Biolaboratories

PI3K p85 alpha Antibody - abx134186 from Abbexa Host Rabbit Clonality Polyclonal

PI3K p85 alpha Antibody - abx134185 from Abbexa Host Mouse Clonality Monoclonal

Anti-PI-3-Kinase-p85-Subunit-alpha-Antibody-clone-U13- - ABD11550 from Abgent, a WuXi AppTec company Prices $311.00 Sizes 2 ml Host Mouse Clonality Monoclonal Clone U13

Anti-PI3K p85 alpha Antibody - CPA9209 from Cohesion Biosciences Prices $110.00, $220.00, $350.00 Sizes 30 µl, 100 µl, 200 µl Host Mouse Clonality Monoclonal

Anti-PI3K p85 alpha Antibody - CPA9434 from Cohesion Biosciences Prices $110.00, $220.00, $350.00 Sizes 30 µl, 100 µl, 200 µl Host Rabbit Clonality Polyclonal

PI3K p85 alpha, Monoclonal Antibody - MBS8241502 from MyBioSource Prices $155.00, $220.00, $295.00 Sizes 30 µl, 100 µl, 200 µl Host Mouse Clonality Monoclonal

Pik3r1 antibody - C-terminal region : Biotin (ARP32121_P050-Biotin) - ARP32121_P050-Biotin from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Pik3r1 antibody - C-terminal region : FITC (ARP32121_P050-FITC) - ARP32121_P050-FITC from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Pik3r1 antibody - C-terminal region : HRP (ARP32121_P050-HRP) - ARP32121_P050-HRP from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Mouse Pik3r1 Antibody - 60-718 from ProSci Prices $375.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

PI3K p85 (5C11) Monoclonal Antibody - bsm-33219M from Bioss Prices $279.50 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 5C11

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