Pik3r1

Gene Symbol Pik3r1
Entrez Gene 18708
Alt Symbol PI3K, p50alpha, p55alpha, p85alpha
Species Mouse
Gene Type protein-coding
Description phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
Other Description PI3-kinase subunit p85-alpha|PI3K regulatory subunit alpha|phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha|phosphatidylinositol 3-kinase regulatory subunit alpha
Swissprots Q8K3B3 P26450
Accessions EDL00772 P26450 AI838690 AK046259 AK049798 BAC33923 AK138868 BAE23803 AK160493 AK164783 BAE37914 AK171366 BB647657 BC002168 AAH02168 BC026146 AAH26146 BC051106 AAH51106 BM963795 BY276314 CB519962 CF169061 M60651 AAA39886 U50413 AAC52847 U50414 AAC52848 XM_006517569 XP_006517632 XM_006517570 XP_006517633 NM_001024955 NP_001020126 NM_001077495 NP_001070963
Function Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (By similarity). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348926). {ECO:0000250, ECO:0000269|PubMed:20348926}.
Top Pathways Apoptosis, VEGF signaling pathway, Focal adhesion, Toll-like receptor signaling pathway, Jak-STAT signaling pathway

Recombinant Mouse Phosphatidylinositol 3-kinase regulatory subunit alpha(Pik3r1) - CSB-YP018003MO CSB-EP018003MO CSB-BP018003MO CSB-MP018003MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Phosphatidylinositol 3-kinase regulatory subunit alpha (Pik3r1), Recombinant Protein - MBS955716 from MyBioSource

Category Protein
Prices $1,530.00, $1,530.00, $1,760.00, $1,760.00, $2,630.00, $2,630.00, $3,070.00, $3,070.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Mouse-Pik3r1-Blocking-Peptide-N-term - BP19794a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg
Species Mouse
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