MLXIP

Gene Symbol	MLXIP
Entrez Gene	22877
Alt Symbol	MIR, MONDOA, bHLHe36
Species	Human
Gene Type	protein-coding
Description	MLX interacting protein
Other Description	MLX-interacting protein|Mlx interactor|class E basic helix-loop-helix protein 36|transcriptional activator MondoA
Swissprots	Q8IXP1 O94945 Q8WYA5 Q7LC47 Q8WVQ0 A7MBN0 Q9HAP2 Q8TAH9
Accessions	EAW98304 EAW98305 EAW98306 Q9HAP2 AB020674 BAA74890 AF245480 AAL55689 AF245481 AAL55690 AF312918 AAG34121 AW996647 BC017656 AAH17656 BC028309 AAH28309 BC039704 AAH39704 BC069272 BC151841 AAI51842 BE207198 BM007462 BM461435 BM558759 BM857835 BQ218664 BQ445885 CA426212 XM_006719290 XP_006719353 XM_006719291 XP_006719354 XM_006719292 XP_006719355 XM_006719293 XP_006719356 XM_006719294 XP_006719357 XR_944508 XR_944509 NM_014938 NP_055753
Function	Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. {ECO:0000250|UniProtKB:Q2VPU4, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}. Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}. Mitochondrion outer membrane {ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}. Note=Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus. {ECO:0000250|UniProtKB:Q2VPU4, ECO:0000269|PubMed:12446771, ECO:0000269|PubMed:16782875}.
Tissue Specificity	Widely expressed in adult tissues. Most abundant in skeletal muscle. {ECO:0000269|PubMed:11073985}.
Top Pathways	Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MLX-interacting protein protein fragment - ab161456 from Abcam Category Protein Source Wheat germ Species Human

MLX-interacting protein peptide - ab90826 from Abcam Category Peptide

MLXIP / MONDOA Antibody Blocking Peptide - LS-E119 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLXIP / MONDOA Antibody Blocking Peptide - LS-E12784 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLXIP / MONDOA Antibody Blocking Peptide - LS-E12785 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MLXIP Protein - H00022877-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MLXIP-Antibody-N-term-Blocking-peptide - BP10228a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human MLXIP protein - orb246627 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

MLX-interacting protein - H00022877-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MLX-interacting protein - H00022877-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MLXIP fusion protein - ag4519 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MLX-interacting protein(MLXIP) ,partial - CSB-YP862054HU CSB-BP862054HU CSB-MP862054HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human MLX-interacting protein - CSB-EP862054HU from Cusabio Category Protein Source E.coli Species Human

MLXIP Recombinant Protein Antigen - NBP1-88617PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MLXIP Peptide - 8547P from ProSci Category Peptide Prices $70.00 Sizes 50 µg Species Human

MLXIP Peptide, Human - M34GP09579H from Creative Peptides Category Peptide Source Synthetic. Species Human

MLXIP Recombinant Protein (OPCA02459) - OPCA02459 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human - AP71517 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

MLX-interacting protein, Recombinant Protein - MBS1470625 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,180.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Recombinant Human MLXIP Protein (1-217 aa), His-SUMO-tagged - MLXIP-1116H from Creative Biomart Category Protein Source E. coli Species Human

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