Gene Symbol | NR2E3 |
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Entrez Gene | 10002 |
Alt Symbol | ESCS, PNR, RNR, RP37, rd7 |
Species | Human |
Gene Type | protein-coding |
Description | nuclear receptor subfamily 2, group E, member 3 |
Other Description | photoreceptor-specific nuclear receptor|retina-specific nuclear receptor |
Swissprots | Q9UHM4 B6ZGU0 Q9Y5X4 |
Accessions | AAD28302 AKE32080 CAB82769 EAW77876 EAW77877 Q9Y5X4 AB307710 BAH02301 AF121129 AAD28301 AF148128 AAF22227 AL711747 AW080977 BC041421 AAH41421 BU732726 HQ692847 ADZ17358 XM_011521146 XP_011519448 NM_014249 NP_055064 NM_016346 NP_057430 NM_001281446 |
Function | Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression. {ECO:0000269|PubMed:15689355, ECO:0000269|PubMed:24069298}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:15689355}. |
Tissue Specificity | Eye specific; found solely in the outer nuclear layer of the adult neurosensory retina, where the nuclei of cone and rod photoreceptors reside. {ECO:0000269|PubMed:15689355}. |
NR2E3 (B-4) - sc-374513 from Santa Cruz Biotechnology
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NR2E3 (H-61) - sc-292264 from Santa Cruz Biotechnology
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NR2E3 (N-13) - sc-46209 from Santa Cruz Biotechnology
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NR2E3 (S-17) - sc-46210 from Santa Cruz Biotechnology
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Anti-NR2E3 antibody - ab123091 from Abcam
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Anti-NR2E3 antibody - ab56922 from Abcam
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Anti-NR2E3 antibody - ab172542 from Abcam
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Anti-NR2E3 antibody - ab172554 from Abcam
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Anti-NR2E3 antibody [H7223] - ab41922 from Abcam
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Anti-NR2E3 / PNR Antibody - LS-C126068 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa170-198, AP) - LS-C216042 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa170-198, APC) - LS-C216043 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa170-198, Biotin) - LS-C216044 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa170-198, FITC) - LS-C216045 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa170-198, PE) - LS-C216047 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa170-198, Azide-free, HRP) - LS-C216046 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (N-Terminus) - LS-C31614 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa169-198) - LS-C323439 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa166-215) - LS-C201252 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody - LS-C334576 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (clone 3D4) - LS-C339874 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (aa170-198) - LS-C162991 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (clone 2F6) - LS-C339880 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (clone 3G3) - LS-C339882 from LifeSpan Bioscience
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Anti-NR2E3 / PNR Antibody (clone 2G3) - LS-C339883 from LifeSpan Bioscience
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