NR2E3

Gene Symbol	NR2E3
Entrez Gene	10002
Alt Symbol	ESCS, PNR, RNR, RP37, rd7
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 2, group E, member 3
Other Description	photoreceptor-specific nuclear receptor|retina-specific nuclear receptor
Swissprots	Q9UHM4 B6ZGU0 Q9Y5X4
Accessions	AAD28302 AKE32080 CAB82769 EAW77876 EAW77877 Q9Y5X4 AB307710 BAH02301 AF121129 AAD28301 AF148128 AAF22227 AL711747 AW080977 BC041421 AAH41421 BU732726 HQ692847 ADZ17358 XM_011521146 XP_011519448 NM_014249 NP_055064 NM_016346 NP_057430 NM_001281446
Function	Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression. {ECO:0000269|PubMed:15689355, ECO:0000269|PubMed:24069298}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:15689355}.
Tissue Specificity	Eye specific; found solely in the outer nuclear layer of the adult neurosensory retina, where the nuclei of cone and rod photoreceptors reside. {ECO:0000269|PubMed:15689355}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NR2E3 full length protein - ab160757 from Abcam Category Protein Source Wheat germ Species Human

NR2E3 / PNR Antibody Blocking Peptide - LS-E3068 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR2E3 / PNR Antibody Blocking Peptide - LS-E29100 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NR2E3 / PNR Antibody Blocking Peptide - LS-E29098 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NR2E3 / PNR Antibody Blocking Peptide - LS-E14088 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PNR/NR2E3 Protein - H00010002-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NR2E3-Antibody-Center-Blocking-Peptide - BP14205c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NR2E3 - H00010002-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NR2E3 - H00010002-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NR2E3 control peptide - SP5292CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

NR2E3 fusion protein - Ag5831 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NR2E3 fusion protein - Ag5503 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human NR2E3, His-tagged - NR2E3-1358H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Photoreceptor Cell Specific Nuclear Receptor (PNR) - RPD956Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Photoreceptor Cell Specific Nuclear Receptor (PNR) - RPD956Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

NR2E3 (transcript variant 2) - TP315425 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NR2E3 (transcript variant 1) - TP320677 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NR2E3 Peptide, Human - M34GP10596H from Creative Peptides Category Peptide Source Synthetic. Species Human

NR2E3 Recombinant Protein (OPCD06302) - OPCD06302 from Aviva Systems Biology Category Protein Source E.coli Species Human

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