NR2E3

Gene Symbol NR2E3
Entrez Gene 10002
Alt Symbol ESCS, PNR, RNR, RP37, rd7
Species Human
Gene Type protein-coding
Description nuclear receptor subfamily 2, group E, member 3
Other Description photoreceptor-specific nuclear receptor|retina-specific nuclear receptor
Swissprots Q9UHM4 B6ZGU0 Q9Y5X4
Accessions AAD28302 AKE32080 CAB82769 EAW77876 EAW77877 Q9Y5X4 AB307710 BAH02301 AF121129 AAD28301 AF148128 AAF22227 AL711747 AW080977 BC041421 AAH41421 BU732726 HQ692847 ADZ17358 XM_011521146 XP_011519448 NM_014249 NP_055064 NM_016346 NP_057430 NM_001281446
Function Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M- and S-cone opsin expression. {ECO:0000269|PubMed:15689355, ECO:0000269|PubMed:24069298}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:15689355}.
Tissue Specificity Eye specific; found solely in the outer nuclear layer of the adult neurosensory retina, where the nuclei of cone and rod photoreceptors reside. {ECO:0000269|PubMed:15689355}.

NR2E3 CRISPR/Cas9 KO Plasmid (h) - sc-405915 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E3 HDR Plasmid (h) - sc-405915-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E3 Double Nickase Plasmid (h) - sc-405915-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E3 Double Nickase Plasmid (h2) - sc-405915-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E3 CRISPR Activation Plasmid (h) - sc-405915-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E3 CRISPR Activation Plasmid (h2) - sc-405915-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E3 Lentiviral Activation Particles (h) - sc-405915-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E3 Lentiviral Activation Particles (h2) - sc-405915-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E3 siRNA (h) - sc-45726 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NR2E3 shRNA Plasmid (h) - sc-45726-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NR2E3 shRNA (h) Lentiviral Particles - sc-45726-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PNR/NR2E3 RNAi - H00010002-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU132771 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15493 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15493 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07166 from Sigma-Aldrich

Category miRNA

NR2E3 siRNA (Human) - CRH6730 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PNR/NR2E3 RNAi - H00010002-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NR2E3 (NM_014249.2) - SHH354768 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NR2E3(NM_016346.2) - SHR020454 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NR2E3(NM_014249.2) - SHR020550 from Creative biogene

Category siRNA
Species Reactivities Human

NR2E3 shRNA Plasmid (Human) - CHH6730 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NR2E3 miRNA 3'UTR clone - MiUTR1H-06902 from Creative biogene

Species Reactivities Human
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